LOS ANGELES CHARGERS (0-1) at BUFFALO (0-1)
Sunday, 1 p.m. ET, CBS
OPENING LINE — Chargers by 7 1/2
RECORD VS. SPREAD — Los Angeles 0-1, Buffalo 0-1
SERIES RECORD — Chargers lead 24-12-2
LAST MEETING — Chargers beat Bills 54-24, Nov. 19, 2017
LAST WEEK — Chargers lost to Chiefs 38-28; Bills lost to Ravens 47-3
AP PRO32 RANKING — Chargers No. 19, Bills No. 32
CHARGERS OFFENSE — OVERALL (1), RUSH (11), PASS (2).
CHARGERS DEFENSE — OVERALL (20), RUSH (13), PASS (22).
BILLS OFFENSE — OVERALL (32), RUSH (25), PASS (32).
BILLS DEFENSE — OVERALL (22), RUSH (19), PASS (21).
STREAKS, STATS AND NOTES — Chargers coach Anthony Lynn served as Bills interim coach for 2016 season finale after Rex Ryan was fired. Lynn was candidate for Bills job before Sean McDermott got it. ... Chargers have won three straight and 17 of past 22 meetings. ... Chargers have outscored Bills by combined 113-44 in past three meetings, and not trailed since 23-14 loss on Oct. 19, 2008. ... QB Philip Rivers is 4-1 against Bills with 1,115 yards passing, 10 touchdowns and one interception. With 424 yards passing against Chiefs, Rivers topped 400 yards for 10th time — tied for fourth on NFL career list. ... RB Melvin Gordon had career-best 102 yards receiving against Chiefs. ... CB Casey Hayward intercepted two of Bills QB Nathan Peterman's five first-half interceptions in last meeting. ... Bills first-round pick QB Josh Allen to make first career start after Peterman went 5 of 18 for 24 yards and two interceptions in two-plus quarters against Ravens. ... Bills traded up five spots to select Allen out of Wyoming — highest in draft order Buffalo has chosen QB. Allen finished 6 of 15 for 74 yards and 26 yards rushing last week. ... Bills only NFL team to not score TD in Week 1. ... RB LeSean McCoy had 22 yards rushing on seven carries, and one catch for minus-1 yard. ... Loss to Ravens was Bills' second-most lopsided margin of defeat, behind 56-10 loss to New England on Nov. 18, 2007. ... Buffalo managed 153 yards offense against Ravens, fewest since 145 in 40-7 loss at Chicago on Oct. 8, 2006. ... Defense allowed Ravens to score six touchdowns on six trips inside 20. ... First-round pick LB Tremaine Edmunds became Bills' first rookie to have sack in season opener since 2002. ... Fantasy Tip: Pick your poison with Rivers and Gordon both having chances of putting up big numbers. Chargers' defense worth consideration against Bills popgun attack and patchwork offensive line.