CFB Pick 'Em: Top Week 2 Games, Including Ohio State-Texas, Michigan-Oklahoma

Was Michigan’s controversial victory against Western Michigan a fluke, or a bad sign for a team about to face No. 11 Oklahoma? Who has the upper hand in the second meeting of Arch Manning and Julian Sayin, when Texas and Ohio State face off in September once more? Which college football teams will show that Week 1 wasn’t a one-time result… for better or worse?

It’s Week 2 of the college football season, which asks those questions and far more — like how No. 6 Oregon will fare against Oklahoma State after a comeback win, or if ACC defending champ Duke can topple Illinois.

Along with answers to those many questions, we have picks for Week 2. Here are our expert picks for the top matchups to watch this college football weekend.

2026 College Football Expert Picks Week 2

 

 

 

2026 College Football Expert Picks Week 2 — 2026 College Football · Week 2

Matchup	RJ Young	Laken Litman	Ben Portnoy	Michael Cohen	Chris Fallica	Sam Panayotovich	Will Hill	Geoff Schwartz
MIZZ@KU
ORE@OKST
OKLA@MICH
ARIZ@BYU
DUKE@ILL
CAL@SYR
MEM@BSU
OSU@TEXAS

Results as of Fri, Sep 11, 6:12 PM EDT

College football Saturday in Week 2 kicks off with a first window of big games, including No. 11 Oklahoma at Michigan and No. 5 Indiana hosting Howard.

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