2025 CFP Title Odds: Indiana Favored Over Miami in National Championship

The College Football Playoff national championship game has officially been set.

Here’s a look at the latest 2025 CFP odds at DraftKings Sportsbook as of Jan. 10.

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No. 10 Miami vs. No. 1 Indiana

Spread: Indiana -7.5
Moneyline: Indiana -325, Oregon +260
O/U: 48.5

Here is what to know about the CFP title oddsboard: 

Miami Rebels on Ole Miss: What an opening semifinal game. Ole Miss entered the fourth quarter of Thursday's tilt with a 17-16 lead over Miami, before the two teams exploded for 25 points in the final frame. The heavyweight slugfest essentially came down to the Hurricanes having the ball for the last extended possession, capping off a 15-play, 75-yard drive with a touchdown and giving the ball back to Ole Miss with just 18 seconds to go. The Canes rushed the ball a whopping 51 times, tallying 191 yards. Compare that to the Rebels who rushed it just 21 times but still amassed 121 yards. Miami also dominated the time of possession, 41:22 to 18:28. Considering all that, what does it say that the Canes still only won by four? Likely that this game could have gone either way and both teams deserved to be here.

Hoosiers Dominate Ducks: It was a much different story in the second semifinal game, as Indiana took down Oregon 56-22 in the Peach Bowl. On the very first play of the game, D'Angelo Ponds intercepted Dante Moore and took it back 25 yards for a touchdown. Moore would drive the Ducks down 75 yards in 14 plays, finding Jamari Johnson for a 19-yard score to make it 7-7 with 7:11 left in the first quarter. That might have been the last point in the game in which Oregon was competitive, as Indiana would go on to score 35 unanswered points to take a 42-7 lead with just under nine minutes in the third quarter. Fernando Mendoza was spectacular, joining Joe Burrow, Mac Jones and Justin Fields as the only players to throw for five TD passes in a CFP game. The 34-point defeat is the largest ever in a bowl game for Oregon, and also the largest loss for them since losing by 46 points to Georgia in 2022. Indiana now has two of the six largest wins in CFP history, and are 7.5-point favorites against Miami. Taking place at Hard Rock Stadium, it'll be the first national title game in the BCS or CFP era in which a team plays in their home stadium. 

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