Panthers vs. Sabres prediction, odds, picks - Oct. 18

Updated Oct. 18, 2025 12:12 p.m. ET

Data Skrive

Aleksander Barkov Jr. and Rasmus Dahlin are two of the most exciting players to keep an eye on when the Florida Panthers meet the Buffalo Sabres at KeyBank Center on Saturday, Oct. 18 at 1 p.m. ET. Take a look at everything you need to know about the Panthers-Sabres game, from the puck lined, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Panthers vs. Sabres Game Information and TV Channel

When: Saturday, October 18, 2025 at 1 p.m. ET
Where: KeyBank Center in Buffalo, New York
TV: ESPN+
Live Boxscore: FOX Sports

Panthers vs Sabres Betting Information
Favorite	Puck Line	Favorite Puck Line Odds	Underdog Puck Line Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Panthers	-1.5	164	-198	6.5	105	-145	-148	+124

Panthers vs. Sabres Prediction

ATS Pick: Sabres (+ 1.5)
O/U Pick: Under (6.5)
Score Prediction: Panthers 4 - Sabres 3

Panthers vs. Sabres Betting Insights

In 45 games last season, Florida and its opponent combined for more than 6.5 goals.
Buffalo played 45 games last season that finished with over 6.5 goals.
These teams scored 6.2 goals per game between them, 0.3 fewer than this one's over/under.
Opponents of these teams averaged 6.2 goals per game combined, 0.3 fewer than this one's total.
In terms of goals scored, the Panthers were 15th in the league, and the Sabres were 10th.
The Sabres were 29th in the league in goals allowed, and the Panthers were seventh.

Panthers Stats

The Panthers' 15 total goals (2.5 per game) rank 11th in the NHL.
Florida ranks 24th in goals against, conceding 17 total goals (2.8 per game) in NHL action.
Their goal differential (-2) ranks 20th in the league.
The six power-play goals Florida has put up this season (on 24 chances) are the second-most in the NHL.
The Panthers are sixth in the league with a 25.00% power-play conversion rate.
Florida has scored one shorthanded goal this season (second among all NHL squads).

Panthers Leaders

Name	Games	Goals	Assists	Points	Giveaways	Takeaways	Faceoff Win %
Brad Marchand	6	3	3	6	2	0	0%
Anton Lundell	6	2	3	5	10	0	60%
Evan Rodrigues	6	2	2	4	9	1	42.6%
Matthew Samoskevich	6	1	2	3	5	1	-
Seth Jones	6	0	3	3	8	1	-

Panthers Player Props

Sabres Stats

With 265 goals (3.2 per game) last season, the Sabres had the NHL's 10th-best offense.
Buffalo allowed 287 total goals (3.5 per game), 29th in the NHL.
With a goal differential of -22, they were 23rd in the league.
Buffalo had 43 power-play goals (21st in NHL) on 229 chances.
The Sabres scored on 18.78% of their power plays, No. 24 in the NHL.
Buffalo had 10 shorthanded goals (fourth in league).