The Biggest NFL Upsets in Week 2 - 2025

The Biggest NFL Upsets in Week 2 - 2025

Updated Sep. 18, 2025 6:33 p.m. ET
Data Skrive

In Week 2 of the 2025 NFL season, how many underdogs emerged victorious? Below, we provide a complete list of the teams that pulled off an upset last week.

Read more about last week's NFL games on FOX Sports!

NFL Week 2's Biggest Upsets

Falcons 22, Vikings 6

  • Spread: Vikings -3.5
  • Total: Under (44.5)
  • Moneyline: Vikings -175, Falcons +145

Seahawks 31, Steelers 17

  • Spread: Steelers -3.5
  • Total: Over (40.5)
  • Moneyline: Steelers -200, Seahawks +165

Buccaneers 20, Texans 19

  • Spread: Texans -2.5
  • Total: Under (42.5)
  • Moneyline: Texans -150, Buccaneers +125

Colts 29, Broncos 28

  • Spread: Broncos -2.5
  • Total: Over (43.5)
  • Moneyline: Broncos -125, Colts +105

Patriots 33, Dolphins 27

  • Spread: Dolphins -2.5
  • Total: Over (43.5)
  • Moneyline: Dolphins -130, Patriots +110

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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