The Biggest NFL Upsets in Week 12 - 2025

In Week 12 of the 2025 NFL season, how many underdogs emerged victorious? Below, we provide a comprehensive list of the teams that pulled off an upset last week.

Read more about last week's NFL games on FOX Sports!

NFL Week 12's Biggest Upsets

Texans 23, Bills 19

• Spread: Bills -5.5
• Total: Under (44.5)
• Moneyline: Bills -275, Texans +225

Cowboys 24, Eagles 21

• Spread: Eagles -3
• Total: Under (47.5)
• Moneyline: Eagles -160, Cowboys +135

Browns 24, Raiders 10

• Spread: Raiders -3
• Total: Under (36)
• Moneyline: Raiders -175, Browns +145

Falcons 24, Saints 10

• Spread: Saints -1.5
• Total: Under (40.5)
• Moneyline: Saints -125, Falcons +105

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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