Texans vs. Colts 2025 Prediction, Odds, Picks - Jan 4

Updated Jan. 4, 2026 12:43 p.m. ET

Data Skrive

The Indianapolis Colts (8-8) will be trying to end a six-game losing streak against the Houston Texans (11-5). The Texans are solid favorites, expected to win by at least a touchdown (currently -9.5). The matchup has an over/under of 38.5 points.

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Texans vs. Colts Odds & Betting Lines

Texans vs Colts Betting Information updated as of January 4, 2026, 12:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Texans	-9.5	-110	-110	38.5	-109	-122

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Texans vs. Colts Prediction & Pick

Pick ATS: Texans (-9.5)
Pick OU: Over (38.5)
Prediction: Texans 28 - Colts 17

How to Watch Houston vs. Indianapolis

Game date: Sunday, January 4, 2026
Time: 1 p.m. ET
Venue: NRG Stadium
Location: Houston, Texas
TV: CBS
Live Boxscore: FOX Sports

Texans vs. Colts Recent Matchups

Over their last five meetings, Houston has tallied four wins versus Indianapolis.
Indianapolis has been outpaced by 2 points in its last five tilts against Houston.

Houston Betting Info

Houston has nine wins in 16 games versus the spread this year.
The Texans have covered the spread once when favored by 9.5 points or more this season (in two opportunities).
Houston games this year have gone over the total in five out of 16 opportunities (31.2%).
When playing as moneyline favorites, the Texans are 6-2 (winning 75% of the time).
Looking at this game's moneyline, the Texans' implied win probability is 84.3%.

Texans Stats

Stat	Average (Total)	Rank
Pass yards	218.9 (3,502)	16
Rush yards	107.4 (1,718)	23
Points scored	22.9 (366)	17
Pass yards against	177.6 (2,842)	4
Rush yards against	94.8 (1,517)	4
Points allowed	16.6 (265)	1

Houston's Key Players

Offense

C.J. Stroud has 2,872 passing yards in 13 games this year, averaging 220.9 per game with a 64.8% completion percentage and 18 touchdowns against eight interceptions.
He has tacked on 204 rushing yards (15.7 per game) without a touchdown on the ground.
Nico Collins has caught 71 passes on 120 targets for 1,117 total yards (eighth in the NFL) and six touchdowns. He is averaging 4.7 catches and 74.5 yards per game in 15 games.
Woody Marks' output on the ground this season includes 655 yards and two TDs. He's averaging 43.7 yards per game and 3.5 per attempt (49th in the NFL).
Marks has totaled 22 catches on 33 targets for 208 yards, with three receiving TDs.
Dalton Schultz has 78 receptions for 704 yards and three touchdowns. He's been targeted 102 times in the passing game, and averages 4.9 receptions and 44.0 yards through 16 games played.

Defense

On defense, Will Anderson Jr. has 12.0 sacks (eighth in the NFL) to go with 19.0 TFL and 48 tackles in 2025.
Danielle Hunter has 52 tackles, 14.0 TFL, and 14 sacks this season.
This season, Kamari Lassiter has recorded 7.0 TFL, 91 tackles, and four interceptions.
Azeez Al-Shaair has 1.0 TFL, 102 tackles, and two interceptions this year.

Indianapolis Betting Info

Indianapolis has covered the spread eight times in 16 games with a set total.
The Colts covered the spread in their only game when underdogs by 9.5 points or more.
Indianapolis games have gone over the total eight times this year.
This season, the Colts have won two out of the seven games in which they've been the underdog.
The bookmakers' moneyline implies a 20.0% chance of a victory for the Colts.

Colts Stats

Stat	Average (Total)	Rank
Pass yards	224.7 (3,595)	12
Rush yards	120.7 (1,931)	14
Points scored	27.3 (436)	8
Pass yards against	250.6 (4,010)	31
Rush yards against	99.9 (1,598)	6
Points allowed	23.4 (374)	19

Indianapolis' Key Players

Offense

Jonathan Taylor averages 97.4 rushing yards per game this year (1,559 total yards to rank second in the NFL), while scoring 18 rushing touchdowns.
On top of his rushing statistics, Taylor has caught 44 passes (on 53 targets) for 365 yards (fifth on the Colts), with two receiving touchdowns. He's averaging 22.8 yards per game.
Michael Pittman Jr. has 78 catches for 773 yards and seven receiving touchdowns. He has been targeted 107 times and averages 4.9 receptions per game in 16 games played.
Alec Pierce has put up 871 receiving yards and four touchdowns on 43 receptions, while being targeted 77 times this season.
Tyler Warren has 791 receiving yards and four touchdowns from 71 receptions after getting 104 targets.

Defense

In 2025, Germaine Pratt has 121 tackles, 6.0 TFL, and one interception over 15 games.
Nick Cross has 2.5 sacks to go with 5.0 TFL, 113 tackles, and one interception.
Zaire Franklin has 113 tackles, 5.0 TFL, two sacks, and five passes defended during the 2025 campaign.
Laiatu Latu has 8.5 sacks (first on the Colts) as well as 12.0 TFL, 43 tackles, and three interceptions.