Texans vs. Colts 2025 Prediction, Odds, Picks - Jan 4

Updated Jan. 2, 2026 8:43 p.m. ET

Data Skrive

Having dropped eight in a row, the Indianapolis Colts (8-8) will face the Houston Texans (11-5). The Texans are big favorites (-10). The expected point total for the matchup is set at 38.5.

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Texans vs. Colts Odds & Betting Lines

Texans vs Colts Betting Information updated as of January 2, 2026, 1:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Texans	-10	-108	-112	38.5	-112	-108

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Texans vs. Colts Prediction & Pick

Pick ATS: Texans (-10)
Pick OU: Over (38.5)
Prediction: Texans 28 - Colts 17

How to Watch Houston vs. Indianapolis

Game date: Sunday, January 4, 2026
Time: 1 p.m. ET
Venue: NRG Stadium
Location: Houston, Texas
TV: CBS
Live Boxscore: FOX Sports

Texans vs. Colts Recent Matchups

In their last five head-to-head matchups, Houston has beaten Indianapolis four times.
Indianapolis has been outpaced by 2 points in its last five tilts against Houston.

Houston Betting Info

Houston has nine wins in 16 games versus the spread this season.
The Texans have covered the spread once when favored by 10 points or more this season (in two opportunities).
Houston games in 2025 have gone over the point total five times in 16 opportunities (31.2%).
The Texans have put together a 6-2 record in games they played as moneyline favorite (winning 75% of those games).
The Texans have an 84.6% chance to win this game, based on the implied probability of the moneyline.

Texans Stats

Stat	Average (Total)	Rank
Pass yards	218.9 (3,502)	16
Rush yards	107.4 (1,718)	24
Points scored	22.9 (366)	16
Pass yards against	177.6 (2,842)	4
Rush yards against	94.8 (1,517)	4
Points allowed	16.6 (265)	1

Houston's Key Players

Offense

C.J. Stroud has 2,872 passing yards in 13 games this year, averaging 220.9 per game with a 64.8% completion percentage and 18 touchdowns against eight interceptions.
In addition to his passing statistics, Stroud also has 204 rushing yards (third on the Texans), but no touchdowns.
Nico Collins has caught 71 passes on 120 targets for 1,117 total yards (eighth in the NFL) and six touchdowns. He is averaging 4.7 catches and 74.5 yards per game through 15 games.
In 15 games, Woody Marks has amassed 655 yards on the ground, averaging 43.7 yards per game and scoring two touchdowns.
Marks has 22 receptions on 33 targets for 208 yards, with three receiving TDs.
Dalton Schultz has 78 catches for 704 yards and three touchdowns. He's been targeted 102 times in the passing game, and averages 4.9 receptions and 44.0 yards in 16 games played.

Defense

On defense, Will Anderson Jr. has 12.0 sacks (eighth in the NFL) to go with 19.0 TFL and 48 tackles in 2025.
Danielle Hunter has 52 tackles, 14.0 TFL, and 14 sacks this season.
This season, Kamari Lassiter has recorded 7.0 TFL, 91 tackles, and four interceptions.
So far this season, Azeez Al-Shaair has 102 tackles, 1.0 TFL, and two interceptions. He leads the Texans in tackles.

Indianapolis Betting Info

Indianapolis has put together an 8-8-0 record against the spread this season.
The Colts have been underdogs by 10 points or more once this year and covered the spread.
Games involving Indianapolis have hit the over on eight occasions this season.
The Colts have been underdogs in seven games this season and won two (28.6%) of those contests.
The oddsmakers' moneyline implies a 19.6% chance of a victory for the Colts.

Colts Stats

Stat	Average (Total)	Rank
Pass yards	224.7 (3,595)	12
Rush yards	120.7 (1,931)	14
Points scored	27.3 (436)	7
Pass yards against	250.6 (4,010)	31
Rush yards against	99.9 (1,598)	5
Points allowed	23.4 (374)	19

Indianapolis' Key Players

Offense

Jonathan Taylor averages 97.4 rushing yards per game this year (1,559 total yards to rank second in the NFL), while scoring 18 rushing touchdowns.
On top of his impact in the run game, Taylor has caught 44 passes (on 53 targets) for 365 yards (fifth on the Colts), with two receiving touchdowns. He's averaging 22.8 yards per game.
Michael Pittman Jr. has 78 catches for 773 yards and seven receiving touchdowns. He has been targeted 107 times and averages 4.9 receptions per game through 16 games played.
Alec Pierce has registered 871 receiving yards and four touchdowns on 43 receptions, while being targeted 77 times on the season.
Tyler Warren has been targeted 104 times, resulting in 71 catches for 791 yards .

Defense

In 2025, Germaine Pratt has put up 6.0 TFL, 121 tackles, and one interception over 15 games.
Nick Cross has 2.5 sacks to go with 5.0 TFL, 113 tackles, and one interception.
Zaire Franklin has 2.0 sacks in addition to his 5.0 TFL and 113 tackles.
Laiatu Latu has intercepted three passes in addition to 43 tackles, 12.0 TFL, 8.5 sacks, and five passes defended.