Seahawks vs. 49ers 2025 Prediction, Odds, Picks - Jan 3

Published Jan. 1, 2026 8:43 p.m. ET

Data Skrive

The Seattle Seahawks (13-3) and San Francisco 49ers (12-4) will face off, with both teams on win streaks -- the Seahawks six in a row, the 49ers six in a row. Seattle is a slight favorite (-1.5). The total for this one is set at 47.5 points.

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Seahawks vs. 49ers Odds & Betting Lines

Seahawks vs 49ers Betting Information updated as of December 31, 2025, 5:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Seahawks	-1.5	-112	-108	47.5	-112	-108

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Seahawks vs. 49ers Prediction & Pick

Pick ATS: Seahawks (-1.5)
Pick OU: Over (47.5)
Prediction: Seahawks 25 - 49ers 23

How to Watch Seattle vs. San Francisco

Game date: Saturday, January 3, 2026
Time: 8 p.m. ET
Venue: Levi's Stadium
Location: Santa Clara, California
TV: ABC/ESPN
Live Boxscore: FOX Sports

Seahawks vs. 49ers Recent Matchups

San Francisco owns a 4-1 record against Seattle in their last five matchups.
Seattle has been outscored by 43 points in its last five tilts versus San Francisco.

Seattle Betting Info

In 16 Seattle games this season, it has 11 wins against the spread.
The Seahawks have an ATS record of 9-4 when playing as at least 1.5-point favorites this season.
Seattle games this year have gone over the total in nine out of 16 opportunities (56.2%).
The Seahawks have won 92.3% of the time they have played as the moneyline favorite (12-1).
The Seahawks have an implied win probability, based on the moneyline, of 55.0%.

Seahawks Stats

Stat	Average (Total)	Rank
Pass yards	231.0 (3,696)	8
Rush yards	119.8 (1,916)	16
Points scored	29.4 (470)	2
Pass yards against	198.6 (3,177)	12
Rush yards against	94.4 (1,510)	3
Points allowed	18.1 (289)	2

Seattle's Key Players

Offense

Jaxon Smith-Njigba has grabbed 113 passes (fourth in the NFL) on 155 targets for 1,709 total yards (first in the NFL) and 10 touchdowns. He is averaging 7.1 catches and 106.8 yards per game through 16 games played.
Sam Darnold has passed for 3,850 yards (fifth in the NFL), 25 touchdowns (seventh in the NFL) and 14 interceptions this year. He is averaging 240.6 yards per game and 8.5 per attempt, while completing 67.2%.
Kenneth Walker III's output on the ground this season includes 930 yards and five TDs. He's averaging 58.1 yards per game and 4.5 per attempt (19th in the NFL).
Walker has picked up 27 catches, 246 yards and zero TDs in the passing game.
Zach Charbonnet has rushed for 656 yards with 11 touchdowns (43.7 yards per game through 15 games).

Defense

On defense, Ernest Jones has five interceptions (second in the NFL) to go with 121 tackles, 4.0 TFL, 0.5 sacks, and seven passes defended in 2025.
Demarcus Lawrence has 52 tackles, 11.0 TFL, and six sacks this season.
This season, Drake Thomas has put up 3.5 sacks (fifth on the Seahawks) to go along with his 10.0 TFL and 83 tackles.
So far this season, Leonard Williams has 62 tackles, 9.0 TFL, and seven sacks.

San Francisco Betting Info

San Francisco is 11-5-0 against the spread this year.
This year, the 49ers have just one ATS win in four games as an underdog of 1.5 points or more.
San Francisco games have gone over the total 10 times this season.
The 49ers have won one of the four games they've played as underdogs this season.
The implied probability of a win by the 49ers based on the moneyline is 49.5%.

49ers Stats

Stat	Average (Total)	Rank
Pass yards	252.3 (4,037)	4
Rush yards	110.3 (1,764)	22
Points scored	27.1 (434)	8
Pass yards against	235.6 (3,770)	25
Rush yards against	103.3 (1,653)	6
Points allowed	22.4 (358)	13

San Francisco's Key Players

Offense

Christian McCaffrey averages 73.7 rushing yards per game this year (1,179 total yards to rank eighth in the NFL), while scoring 10 rushing touchdowns.
On top of his rushing statistics, McCaffrey has caught 96 passes (on 122 targets) for 890 yards (first on the 49ers), with seven receiving touchdowns. He's averaging 55.6 yards per game.
In eight games, Brock Purdy has 2,040 passing yards, while throwing 20 touchdowns against nine interceptions and completing 69.3% of his attempts.
Purdy also has three rushing touchdowns and 126 rushing yards (third on the 49ers).
Mac Jones has thrown for 2,151 yards this year, 13 touchdowns and six interceptions. He is completing 69.6% of his passes while averaging 195.5 yards per game and 7.4 per attempt.
Jauan Jennings has 608 receiving yards and nine touchdowns (seventh in the NFL) from 51 receptions after getting 84 targets.

Defense

Dee Winters has intercepted one pass to go with 99 tackles, 8.0 TFL, and five passes defended in 2025.
Upton Stout's stat sheet includes 76 tackles, 4.0 TFL, one sack, and five passes defended.
Ji'Ayir Brown has 2.0 TFL, 55 tackles, and two interceptions.
Tatum Bethune has registered 3.0 TFL and 84 tackles over 11 games.