Rams vs. Titans 2025 Prediction, Odds, Picks - Sep 14

The Los Angeles Rams (1-0) are favored by 5.5 points versus the Tennessee Titans (0-1) on September 14, 2025, starting at 1 p.m. ET, airing on CBS. The expected point total for the matchup is set at 41.5.

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Rams vs. Titans Odds & Betting Lines

Rams vs. Titans Prediction & Pick

• Pick ATS: Rams (-5.5)
  
• Pick OU: Over (41.5)
  
• Prediction: Rams 28 - Titans 16

How to Watch Los Angeles vs. Tennessee

• Game date: Sunday, September 14, 2025
• Time: 1 p.m. ET
• Venue: Nissan Stadium
• Location: Nashville, Tennessee
• TV: CBS
• Live Boxscore: FOX Sports

Rams vs. Titans Recent Matchups

• In their past two matchups, Tennessee holds a split 1-1 record against Los Angeles.
• Over their last two head-to-head matchups, Tennessee has racked up 51 points, while Los Angeles has posted 43.

Los Angeles Betting Info

• Los Angeles put together a 9-8-0 record against the spread last season.
• The Rams had no wins ATS (0-2) as a 5.5-point favorite or more last season.
• Last season, eight Los Angeles games hit the over.
• The Rams won 85.7% of the games last season when they were favored on the moneyline (6-1).
• Los Angeles played as a moneyline favorite of -250 or shorter in only two games last season, and it won both.
• The Rams have an implied moneyline win probability of 71.4% in this matchup.

Rams Stats (2024)

Los Angeles' Key Players

Offense

• Kyren Williams averaged 81.2 rushing yards per game last year (1,299 total yards to rank seventh in the NFL,) while scoring 14 rushing touchdowns.
• Williams also figured into the passing attack with 182 yards (11.4 per game) on 34 receptions (2.1 per game), while being targeted 40 times. He had two receiving touchdowns.
• Matthew Stafford had 3,762 passing yards, 20 touchdowns and eight interceptions. His completion percentage was 65.8% and he averaged 235.1 yards per game and 7.3 per attempt.
• Last season, Davante Adams caught 85 passes for 1,063 receiving yards with eight touchdowns through the air. He was targeted 141 total times and averaged 6.1 receptions per game over 14 games played.
• Puka Nacua had 990 receiving yards and three touchdowns from 79 receptions on 106 targets.

Defense

• Jared Verse had 66 tackles, 11.0 TFL, 4.5 sacks, and two passes defended in 2024.
• Quentin Lake had 111 tackles, 1.0 TFL, two sacks, and five passes defended.
• Kobie Turner had 62 tackles, 10.0 TFL, eight sacks, and four passes defended in the 2024 season.
• Byron Young's stats included 62 tackles, 12.0 TFL, 7.5 sacks, and one pass defended in 17 games

Tennessee Betting Info

• Tennessee won just two games against the spread last year.
• The Titans won once ATS (1-6) as underdogs of 5.5 points or more last year.
• In Tennessee games last season, combined scoring went over the point total 10 times.
• Last season, the Titans won two out of the 12 games, or 16.7%, in which they were the underdog.
• Tennessee was 1-4 last season when entering a game as the underdog by +205 or more on the moneyline.
• The Titans have a 32.8% chance to win this game based on the implied probability of the moneyline.

Titans Stats (2024)

Tennessee's Key Players

Offense

• Last year in 16 games, Tony Pollard racked up 1,079 yards rushing and scored five rushing TDs. He averaged 67.4 yards per game and 4.2 per carry (27th in NFL).
• Pollard's contributions included 41 catches (2.6 per game) on 57 targets for 238 yards (14.9 per game). He did not score a TD in the passing game.
• Calvin Ridley had 64 receptions for 1,017 yards and four receiving TDs. He was targeted 120 times and averaged 3.8 catches in 17 games.
• Last season for the Seahawks, Tyler Lockett caught 49 passes for 600 yards with two TDs . He was targeted 74 times, and averaged 2.9 receptions in 17 games.
• Chigoziem Okonkwo had 52 receptions for 479 yards and two TDs. He averaged 3.3 yards per game in 16 games and was targeted 70 times.

Defense

• Xavier Woods picked off three passes to go with 119 tackles, 2.0 TFL, and six passes defended for the Panthers in 2024.
• Jeffery Simmons posted 76 tackles, 11.0 TFL, and five sacks.
• Cody Barton had 1.5 sacks plus 2.0 TFL, 104 tackles, and two interceptions for the Broncos.
• Amani Hooker put up 4.0 TFL, 70 tackles, and five interceptions over 14 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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