Patriots vs. Browns 2025 Prediction, Odds, Picks - Oct 26

The New England Patriots (5-2) will be trying to continue a four-game winning streak against the Cleveland Browns (2-5). The Patriots are solid favorites, expected to win by at least a touchdown (currently -7). The predicted point total for the matchup is 40.5.

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Patriots vs. Browns Odds & Betting Lines

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Patriots vs. Browns Prediction & Pick

• Pick ATS: Patriots (-7)
  
• Pick OU: Over (40.5)
  
• Prediction: Patriots 27 - Browns 14

How to Watch New England vs. Cleveland

• Game date: Sunday, October 26, 2025
• Time: 1 p.m. ET
• Venue: Gillette Stadium
• Location: Foxborough, Massachusetts
• TV: Watch on FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Patriots vs. Browns Recent Matchups

• Over their last three meetings, New England has totaled three wins versus Cleveland.
• In their last three head-to-head matchups, New England has tallied 110 points against Cleveland, while giving up only 35 points.

New England Betting Info

• Against the spread, New England is 5-2-0 this year.
• New England contests this year have hit the over 42.9% of the time (three times in seven games with a set point total).
• When playing as moneyline favorites, the Patriots are 3-1, winning 75% of the time.
• The implied probability for this matchup, considering the moneyline, gives the Patriots a 79.2% chance to win.

Patriots Stats

New England's Key Players

Offense

• Drake Maye ranks eighth in the NFL with 1,744 passing yards in seven games this year, averaging 249.1 per game with a 75.2% completion percentage and 12 touchdowns (eighth in the NFL) against two interceptions.
• In addition to his passing statistics, Maye also has 200 rushing yards (second on the Patriots), with two rushing touchdowns.
• Kayshon Boutte has 20 receptions for 356 yards and four TDs. Through seven games, he is averaging 2.9 catches and 50.9 yards per game.
• Rhamondre Stevenson's output on the ground this season includes 245 yards and three TDs. He is averaging 35 yards per game and 3.6 per attempt (36th in the NFL).
• Stevenson has totaled 15 receptions on 17 targets for 154 yards, though he has not scored a touchdown in the passing game.
• Hunter Henry has 24 receptions for 310 yards and three touchdowns. He's been targeted 36 times in the air attack, and averages 3.4 receptions and 44.3 yards in seven games played.

Defense

• On the defensive side for the Patriots, Harold Landry has powered the unit with 27 tackles, seven TFL, and 5.5 sacks in 2025.
• Robert Spillane has 53 tackles, one TFL, one sack, and one interception this season. His tackle total leads the Patriots.
• Marcus Jones has collected 30 tackles, five TFL, one sack, and two interceptions this year. He's fourth on the Patriots in tackles.
• So far this season, Christian Elliss has 38 tackles. He's second on the Patriots in tackles.

Cleveland Betting Info

• Cleveland has put together a record of 3-4-0 against the spread this year.
• The Browns have been underdogs by 7 points or more three times this year and covered the spread once.
• Cleveland games have gone over the total three times this season.
• This season, the Browns have won one out of the six games in which they've been the underdog.
• The implied probability of a win by the Browns based on the moneyline is 25.0%.

Browns Stats

Cleveland's Key Players

Offense

• Quinshon Judkins averages 77.8 rushing yards per game this year (467 total yards), while scoring five rushing touchdowns.
• Judkins has also played a role the passing attack with 62 yards (10.3 per game) on nine receptions (1.5 per game), while being targeted 12 times. He is still trying for his first receiving touchdown.
• Dillon Gabriel has 546 passing yards, three touchdowns and zero interceptions. His completion percentage is 59.8% and he averages 109.2 yards per game and 5.1 per attempt.
• Harold Fannin has registered 290 receiving yards and one touchdown on 32 receptions, while being targeted 43 times on the season.
• David Njoku has 223 receiving yards and one touchdown from 23 receptions after getting 36 targets.

Defense

• Myles Garrett has amassed five sacks (first on the Browns) to go with 10 TFL and 25 tackles through seven games in 2025.
• Tyson Campbell has registered one TFL, 41 tackles, and one interception through seven games.
• Devin Bush Jr. has recorded one sack (fourth on the Browns) as well as four TFL and 51 tackles in the 2025 campaign.
• Carson Schwesinger has 54 tackles, four TFL, and one sack.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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