NFL Week 6 Predictions, Betting Odds & TV Schedule

The contests in a Week 6 NFL lineup that shouldn't be missed include the San Francisco 49ers squaring off against the Cleveland Browns at Cleveland Browns Stadium.

Here are the betting odds to dissect prior to Week 6 in the NFL.

Week 6 Betting Lines & Game Info

Kansas City Chiefs vs. Denver Broncos

Odds & Prediction

• Spread: Chiefs (-10.5)
• Moneyline: Chiefs -633, Broncos +458
• Total: 47.5 points
• Prediction: Chiefs 40, Broncos 11

How to Watch

• Game Date: Thursday, October 12
• Game Time: 8:15 PM ET
• TV Channel: Amazon Prime Video
• Location: Kansas City, Missouri

Tennessee Titans vs. Baltimore Ravens

Odds & Prediction

• Spread: Ravens (-5.5)
• Moneyline: Ravens -250, Titans +203
• Total: 42.5 points
• Prediction: Ravens 23, Titans 13

How to Watch

• Game Date: Sunday, October 15
• Game Time: 9:30 AM ET
• TV Channel: NFL Network
• Location: London, United Kingdom

Atlanta Falcons vs. Washington Commanders

Odds & Prediction

• Spread: Falcons (-1.5)
• Moneyline: Falcons -127, Commanders +107
• Total: 42 points
• Prediction: Falcons 31, Commanders 14

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Atlanta, Georgia

Miami Dolphins vs. Carolina Panthers

Odds & Prediction

• Spread: Dolphins (-14)
• Moneyline: Dolphins -1044, Panthers +667
• Total: 47.5 points
• Prediction: Dolphins 35, Panthers 20

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Miami Gardens, Florida

Jacksonville Jaguars vs. Indianapolis Colts

Odds & Prediction

• Spread: Jaguars (-4)
• Moneyline: Jaguars -203, Colts +168
• Total: 44 points
• Prediction: Jaguars 24, Colts 20

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Jacksonville, Florida

Chicago Bears vs. Minnesota Vikings

Odds & Prediction

• Spread: Vikings (-3)
• Moneyline: Vikings -162, Bears +138
• Total: 44.5 points
• Prediction: Vikings 27, Bears 23

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Chicago, Illinois

Houston Texans vs. New Orleans Saints

Odds & Prediction

• Spread: Saints (-2.5)
• Moneyline: Saints -137, Texans +116
• Total: 42 points
• Prediction: Texans 25, Saints 14

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Houston, Texas

Cleveland Browns vs. San Francisco 49ers

Odds & Prediction

• Spread: 49ers (-9.5)
• Moneyline: 49ers -515, Browns +383
• Total: 36 points
• Prediction: 49ers 26, Browns 15

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Cleveland, Ohio

Cincinnati Bengals vs. Seattle Seahawks

Odds & Prediction

• Spread: Bengals (-3)
• Moneyline: Bengals -154, Seahawks +131
• Total: 45.5 points
• Prediction: Seahawks 24, Bengals 21

How to Watch

• Game Date: Sunday, October 15
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Cincinnati, Ohio

Las Vegas Raiders vs. New England Patriots

Odds & Prediction

• Spread: Raiders (-3)
• Moneyline: Raiders -152, Patriots +128
• Total: 41.5 points
• Prediction: Raiders 25, Patriots 13

How to Watch

• Game Date: Sunday, October 15
• Game Time: 4:05 PM ET
• TV Channel: CBS
• Location: Paradise, Nevada

Los Angeles Rams vs. Arizona Cardinals

Odds & Prediction

• Spread: Rams (-7)
• Moneyline: Rams -340, Cardinals +264
• Total: 48 points
• Prediction: Rams 31, Cardinals 16

How to Watch

• Game Date: Sunday, October 15
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Inglewood, California

Tampa Bay Buccaneers vs. Detroit Lions

Odds & Prediction

• Spread: Lions (-3)
• Moneyline: Lions -162, Buccaneers +137
• Total: 43.5 points
• Prediction: Lions 23, Buccaneers 21

How to Watch

• Game Date: Sunday, October 15
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Tampa, Florida

New York Jets vs. Philadelphia Eagles

Odds & Prediction

• Spread: Eagles (-6.5)
• Moneyline: Eagles -303, Jets +240
• Total: 43 points
• Prediction: Eagles 26, Jets 18

How to Watch

• Game Date: Sunday, October 15
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: East Rutherford, New Jersey

Buffalo Bills vs. New York Giants

Odds & Prediction

• Spread: Bills (-15.5)
• Moneyline: Bills -1355, Giants +788
• Total: 43.5 points
• Prediction: Bills 38, Giants 8

How to Watch

• Game Date: Sunday, October 15
• Game Time: 8:20 PM ET
• TV Channel: NBC
• Location: Orchard Park, New York

Los Angeles Chargers vs. Dallas Cowboys

Odds & Prediction

• Spread: Cowboys (-1)
• Moneyline: Cowboys -124, Chargers +103
• Total: 50 points
• Prediction: Chargers 25, Cowboys 24

How to Watch

• Game Date: Monday, October 16
• Game Time: 8:15 PM ET
• TV Channel: ABC/ESPN
• Location: Inglewood, California