How to Watch 49ers vs. Jaguars: Time, TV Channel and Live Stream – 2025 Week 4

Two excellent runners will be on display when Christian McCaffrey and the San Francisco 49ers (3-0) host Travis Etienne and the Jacksonville Jaguars (2-1) on Sunday, September 28, 2025.

The 49ers rank seventh in total offense this year (361 yards per game), but they've been thriving on defense, ranking fourth-best in the NFL with 361 yards allowed per game. The Jaguars have been keeping opposing offenses in check on the defensive side of the ball, surrendering only 17 points per game (fifth-best). On offense, they rank 14th by posting 23.3 points per game.

Below we dig deep into all of the details you need to know about this contest, including how to watch on TV.

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How to Watch 49ers vs. Jaguars

• When: Sunday, September 28, 2025 at 4:05 p.m. ET
• Where: Levi's Stadium in Santa Clara, California
• TV: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Learn more about the San Francisco 49ers vs. the Jacksonville Jaguars on FOX Sports!

49ers vs. Jaguars: Head-to-Head

• Against Jacksonville, San Francisco has collected three wins over the past three matchups.
• San Francisco has scored 108 points in the last three matchups while only allowing 46 to Jacksonville.

49ers' 2025 Schedule

49ers Stats & Insights

• San Francisco has been making things happen on both sides of the ball in the passing game this year, ranking best in passing (271.3 passing yards per game) and fifth-best in passing defense (162 passing yards allowed per game).
• The 49ers are putting up 89.7 rushing yards per game offensively this season (26th in NFL), and they are giving up 103.7 rushing yards per game (15th) on the other side of the ball.
• San Francisco ranks 20th in the league with a -1 turnover margin after forcing 3 turnovers (14th in the NFL) and committing four (17th in the NFL).

49ers Key Players

• McCaffrey has been getting things done on the ground, rushing for 176 yards and zero touchdowns in three games.
• Mac Jones has suited up for two games in 2025, and he's accumulated 563 passing yards, four touchdowns, one interception and a 66.3% completion percentage.
• Ricky Pearsall has been a key part of the 49ers' passing attack in 2025, posting 16 catches for 281 yards and zero touchdowns.

Jaguars' 2025 Schedule

Jaguars Stats & Insights

• From an offensive standpoint, Jacksonville is accumulating 214.7 passing yards per contest (13th-ranked). It ranks 17th in the NFL defensively (209.3 passing yards surrendered per game).
• In terms of rushing, the Jaguars have been productive on both sides of the ball this season, ranking fifth-best in rushing yards per game (141.7) and fourth-best in rushing yards surrendered per game (82.7).
• Jacksonville has fared really well in terms of turnovers, as the team's turnover margin of +5 ranks second-best in the NFL, with nine forced turnovers (second in league) and four turnovers committed (17th in league).

Jaguars Key Players

• In three games, Etienne has rushed for 270 yards (90.0 per game) and one touchdown.
• In three games, Trevor Lawrence has passed for 671 yards (223.7 per game), with four touchdowns and four interceptions, and a completion percentage of 55.8%.
• On the ground, Bhayshul Tuten has scored one touchdown and accumulated 74 yards (24.7 per game).

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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