Buccaneers vs. Cardinals 2025 Prediction, Odds, Picks - Nov 30

The Tampa Bay Buccaneers (6-5) and Arizona Cardinals (3-8) will face off, with both teams on losing streaks -- the Buccaneers three in a row, the Cardinals three in a row. Tampa Bay is the favorite (currently -3.5). The expected point total for the matchup is set at 44.5.

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Buccaneers vs. Cardinals Odds & Betting Lines

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Buccaneers vs. Cardinals Prediction & Pick

• Pick ATS: Buccaneers (-3.5)
  
• Pick OU: Over (44.5)
  
• Prediction: Buccaneers 29 - Cardinals 19

How to Watch Tampa Bay vs. Arizona

• Game date: Sunday, November 30, 2025
• Time: 1 p.m. ET
• Venue: Raymond James Stadium
• Location: Tampa, Florida
• TV: Watch on FOX
• Streaming: FOX One (Limited time offer: 50% off the first two months)

Buccaneers vs. Cardinals Recent Matchups

• Tampa Bay owns a 2-1 record against Arizona in their last three matchups.
• Over their last three head-to-head contests, Tampa Bay has scored 82 points, while Arizona has compiled 81.

Tampa Bay Betting Info

• Tampa Bay is 5-6-0 against the spread this year.
• The Buccaneers have been favored by 3.5 points or more three times this season, and covered the spread in two of those matchups.
• Tampa Bay games this year have gone over the total in six out of 11 opportunities (54.5%).
• When playing as moneyline favorites, the Buccaneers are 4-1 (winning 80% of the time).
• The Buccaneers have a 67.2% chance to win this game, based on the implied probability of the moneyline.

Buccaneers Stats

Tampa Bay's Key Players

Offense

• Baker Mayfield has passed for 2,406 yards, 18 touchdowns and five interceptions this year. He averages 218.7 yards per game and 6.7 per attempt, while completing 62.7% of his passes.
• To go along with his passing statistics, Mayfield also has 216 rushing yards (fourth on the Buccaneers), with one rushing touchdown.
• Emeka Egbuka has caught 48 passes on 93 targets for 749 total yards and six touchdowns. He is averaging 4.4 catches and 68.1 yards per game in 11 games.
• Rachaad White has 414 rushing yards with four touchdowns (37.6 yards per game across 11 games).
• White has picked up 29 catches, 148 yards and zero TDs in the passing game.
• In the ground game, Sean Tucker averages 4.4 yards per attempt and 25.2 yards per game for 277 total rushing yards. He has recorded four rushing touchdowns this season.
• He has added eight catches (on 10 targets) for 34 receiving yards with one touchdown. He's averaging 3.1 receiving yards and 0.7 receptions per game.

Defense

• On the defensive side for the Buccaneers, Tykee Smith has powered the unit with 85 tackles, six TFL, two sacks, and one interception in 2025.
• Lavonte David has intercepted one pass and has added 78 tackles, seven TFL, 2.5 sacks, and two passes defended.
• SirVocea Dennis has put up 71 tackles, seven TFL, two sacks, and one interception this year.
• This season, Antoine Winfield Jr. has 56 tackles, four TFL, one sack, and one interception.

Arizona Betting Info

• Arizona has covered the spread five times over 11 games with a set total.
• So far this year, the Cardinals have been installed as underdogs by a 3.5-point margin or more five times and are 3-2 ATS in those games.
• This year, Arizona games have hit the over seven times.
• This season, the Cardinals have been the underdog eight times and won one of those games.
• The implied probability of a win by the Cardinals based on the moneyline is 37.0%.

Cardinals Stats

Arizona's Key Players

Offense

• Jacoby Brissett has thrown for 1,887 yards this year, with 11 touchdowns and three interceptions. He is completing 66.8% of his attempts while averaging 235.9 yards per game and 7.2 per attempt.
• Brissett has also rushed for one touchdown and 100 yards (sixth on the Cardinals).
• Trey McBride has 80 catches (third in the NFL) for 797 yards (eighth in the NFL) and seven receiving touchdowns (fourth in the NFL). He has been targeted 109 times and averages 7.3 receptions per game in 11 games played.
• Through nine games played this season, Marvin Harrison Jr. has 34 catches (3.8 receptions per game on 6.9 targets per game) for 525 yards and four receiving touchdowns.
• Michael Wilson has 534 receiving yards and one touchdown from 47 receptions after getting 71 targets.

Defense

• Josh Sweat has 21 tackles, 11 TFL, nine sacks, and two passes defended in 2025.
• Akeem Davis-Gaither has one interception on top of 58 tackles, two TFL, and four passes defended.
• Jalen Thompson has 72 tackles, two TFL, one sack, and four passes defended during the 2025 season.
• Budda Baker's stat sheet includes one interception as well as 78 tackles, one TFL, 0.5 sacks, and three passes defended in 11 games

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Tampa Bay Buccaneers

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