Mavericks vs. Spurs Prediction, Odds, Picks - Oct. 22

The San Antonio Spurs start their 2025-26 NBA season on October 22, 2025, going up against the Dallas Mavericks at American Airlines Center. The Mavericks square off with the Spurs in a game that Dallas is currently a modest favorite by 3 points. The matchup has an over/under of 223.5.

Here's everything you need to know about the Mavericks-Spurs game, from the point spread, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Mavericks vs. Spurs Game Information, TV Channel & Odds

• When: Wednesday, October 22, 2025 at 9:30 p.m. ET
• Where: American Airlines Center in Dallas, Texas
• TV: ESPN
• Live Boxscore: FOX Sports

Mavericks vs. Spurs Prediction

ATS Pick: Mavericks (- 3)
O/U Pick: Over (223.5)
Score Prediction: Mavericks 118 - Spurs 112

Mavericks vs. Spurs Betting Insights

• The Mavericks' 82 games last season went over this contest's total of 223.5 points 49 times.
• The Spurs played 51 games last season that ended with a point total higher than 223.5 points.
• These teams racked up a combined 228.1 points per game last season, 4.6 more points than this matchup's point total.
• Combined, these teams allowed 232.1 points per contest last year, 8.6 more points than the over/under for this game.
• Mavericks outings last season had an average total of 228.0, 4.5 more points than this game's over/under.
• The Spurs had a 228.5-point average over/under in their contests last year, 5.0 more points than the point total for this game.

Mavericks Recent Trends

• Dallas won 38 games against the spread last season, while failing to cover or pushing 44 times.
• Dallas was 16-13 ATS last season when playing as at least a 3-point favorite.
• Last season, the combined scoring went over the point total 46 times in Dallas' games.
• Last year, the Mavericks recorded only 2.5 fewer points per game (114.2) than the Spurs allowed (116.7).
• Dallas went 25-10-2 against the spread and 27-10 overall last season when scoring more than 116.7 points.
• Last season, the Mavericks had a 47.9% shooting percentage from the field, which was 0.5% higher than the 47.4% of shots the Spurs' opponents knocked down.
• The Mavericks owned a better record against the spread in home games (19-20-1) than they did on the road (19-22-1) last season.
• Dallas exceeded the total less consistently when playing at home last year, hitting the over in 18 of 40 home matchups (45%). In road games, it hit the over in 28 of 42 games (66.7%).
• As a moneyline favorite, the Mavericks won a higher percentage of their games at home (.696) compared to road games (.538) last season.

Mavericks Recent Stats

Mavericks Leaders

• Anthony Davis averaged 24.7 points, 11.6 rebounds and 3.5 assists last season. He also sank 51.6% of his shots from the floor.
• Kyrie Irving's numbers last season were 24.7 points, 4.8 boards and 4.6 assists per contest. He made 47.3% of his shots from the floor and 40.1% from 3-point range, with an average of 2.9 triples.
• P.J. Washington Jr. recorded 14.7 points, 7.8 rebounds and 2.3 assists per game, plus 1.1 steals and 1.1 blocks.
• Naji Marshall recorded 13.2 points, 4.8 boards and 3.0 assists per game, plus 1.0 steal and 0.2 blocks.
• Klay Thompson's numbers last season were 14.0 points, 3.4 boards and 2.0 assists per contest. He sank 41.2% of his shots from the field and 39.1% from 3-point range, with an average of 3.0 triples.

Mavericks Player Props

Spurs Recent Trends

• The Spurs covered 39 times in 82 chances against the spread last season.
• San Antonio's ATS record as an underdogs by 3 points or greater was 19-25 last year.
• Last season, 46 of the Spurs' games went over the point total.
• The Spurs' 113.9 points per game last year were just 1.5 fewer points than the 115.4 the Mavericks gave up.
• San Antonio put together a 21-12 ATS record and a 24-9 overall record last season in games it scored more than 115.4 points.
• The Spurs shot 46.5% from the field, 0.4% lower than the 46.9% the Mavericks' opponents shot last season.
• Against the spread, the Spurs performed better at home (21-20-0) than on the road (18-23-0) last season.
• San Antonio's games went above the over/under more often at home (24 times out of 41) than away (22 of 41) last season.
• The Spurs' winning percentage at home as moneyline favorites was .688 (11-5) last year, and away it was .750 (6-2).

Spurs Recent Stats

Spurs Leaders

• De'Aaron Fox scored 23.5 points and distributed 6.3 assists per game last season.
• Victor Wembanyama averaged 11.0 boards per game in addition to his 24.3 PPG average.
• Julian Champagnie knocked down shots from beyond the arc at a clip of 2.2 per contest a season ago.
• Fox averaged 1.5 takeaways per game, while Wembanyama compiled 3.8 rejections per contest.

Spurs Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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