Twins vs. Diamondbacks Prediction, Odds, Picks - September 13

Geraldo Perdomo and the Arizona Diamondbacks take the field on Saturday at Target Field against Joe Ryan, who is starting for the Minnesota Twins. First pitch will be at 7:10 p.m. ET. Oddsmakers list the Twins as -146 moneyline favorites, while giving the underdog Diamondbacks +122 moneyline odds to win. Minnesota is the favorite on the run line (-1.5 with +149 odds). An 8.5-run over/under has been listed in this contest.

Take a look at everything you need from a betting perspective on the Twins-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Twins vs. Angels Highlights | MLB on FOX

Check out the best moments between the Minnesota Twins and the Los Angeles Angels.

Twins vs. Diamondbacks Game Information & Odds

• When: Saturday, September 13, 2025 at 7:10 p.m. ET
• Where: Target Field in Minneapolis, Minnesota
• How to watch on TV: MNNT and ARID

Twins vs. Diamondbacks Prediction

• Score Prediction: Twins 5, Diamondbacks 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Twins 50%, Diamondbacks 50%

Twins vs. Diamondbacks Betting Insights

• This season, the Twins have won 39 out of the 84 games, or 46.4%, in which they've been favored.
• Minnesota has a record of 18-14, a 56.2% win rate, when favored by -146 or more by oddsmakers this season.
• Bookmakers have implied with the moneyline set for this matchup that the Twins have a 59.3% chance to win.
• The Diamondbacks have been victorious in 30, or 47.6%, of the 63 contests they have been chosen as underdogs in this season.
• This season, Arizona has come away with a win 16 times in 26 chances when named as an underdog of at least +122 or longer on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Diamondbacks have a 45% chance of pulling out a win.

Twins Recent Betting Performance

• The Twins went 1-5 across the six games they were moneyline favorites in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Twins combined with their opponents to go over the total six times.
• The Twins are 4-6-0 against the spread over their past 10 games.

Twins Recent Stats

Twins Player Insights

• Byron Buxton leads the Twins with 31 home runs and 76 runs batted in, while putting up a team-best batting average of .274.
• Of all batters in the majors, Buxton's home run total places him 11th, and his RBI tally ranks him 48th.
• Buxton has collected a hit in five games in a row. During his last five outings he is batting .375 with a triple, two home runs, a walk and four RBIs.
• Trevor Larnach is batting .254 with 21 doubles, a triple, 16 home runs and 49 walks.
• Larnach ranks 111th in homers and 111th in RBI in the bigs.
• Brooks Lee is batting .237 with 14 doubles, a triple, 14 home runs and 29 walks.
• Kody Clemens is batting .213 with 11 doubles, three triples, 19 home runs and 25 walks.

Twins Team Props

Diamondbacks Recent Betting Performance

• The Diamondbacks have played as underdogs in six of their past 10 games and have gone 3-3 in those contests.
• In their last 10 games with a total, the Diamondbacks and their opponents are 6-4-0 when it comes to hitting the over.
• The Diamondbacks have six wins against the spread in their last 10 chances.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Perdomo has put up a team-leading batting average of .285 while leading the Diamondbacks in runs batted in with a mark of 95.
• Perdomo's home run total puts him 79th in MLB, and he ranks 12th in RBI.
• Perdomo has collected a hit in three games in a row. During his last five outings he is hitting .235 with two home runs, four walks and four RBIs.
• Corbin Carroll has put his power on display as he paces his team with 30 home runs.
• Carroll ranks 13th overall in home runs and 48th in RBI this season.
• Ketel Marte has 22 doubles, 25 home runs and 63 walks while batting .281.
• Gabriel Moreno has 11 doubles, a triple, nine home runs and 20 walks while hitting .290.

Diamondbacks Team Props

Twins vs. Angels Highlights | MLB on FOX

Check out the best moments between the Minnesota Twins and the Los Angeles Angels.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

Minnesota Twins

Arizona Diamondbacks