Tigers vs. Cardinals Prediction, Odds, Picks - May 20

The St. Louis Cardinals and Alec Burleson take the field against Gleyber Torres and the Detroit Tigers on Tuesday, in the second game of a three-game series at Busch Stadium. The Cardinals are listed as +149 moneyline underdogs in this matchup against the Tigers (-179). Detroit is the favorite on the run line (-1.5). The over/under for the matchup has been set at 7.5 runs.

Here's everything you need from a betting perspective on the Tigers-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

Keep up with MLB on FOX Sports.

Tigers vs. Cardinals Highlights | MLB on FOX

Check out the top moments from this MLB game between the Detroit Tigers and the St. Louis Cardinals!

Tigers vs. Cardinals Game Information & Odds

• When: Tuesday, May 20, 2025 at 7:45 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMW and FDSDET

Tigers vs. Cardinals Prediction

• Score Prediction: Cardinals 5, Tigers 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Tigers 52%, Cardinals 48%

Tigers vs. Cardinals Betting Insights

• This season, the Tigers have won 21 out of the 28 games, or 75%, in which they've been favored.
• Detroit has a record of 8-2, a 80% win rate, when favored by -179 or more by sportsbooks this season.
• Bookmakers have implied with the moneyline set for this matchup that the Tigers have a 64.2% chance to win.
• The Cardinals have won in 18, or 56.2%, of the 32 contests they have been named as odds-on underdogs this year.
• St. Louis has yet to win this season when listed as an underdog of +149 or worse on the moneyline this season.
• The moneyline set for this matchup implies the Cardinals have a 40.2% chance of walking away with the win.

Tigers Recent Betting Performance

• The Tigers have a 4-2 record from the six games they were moneyline favorites over their last 10 matchups.
• In their last 10 matchups (all 10 of them had set totals), the Tigers and their opponents combined to hit the over five times.
• The Tigers' ATS record is 3-7-0 over their past 10 games.

Tigers Recent Stats

Tigers Player Insights

• The Tigers' best power option comes in the form of Spencer Torkelson and his 12-home-run 38-RBI season, both team highs.
• Torkelson is eighth in homers and fourth in RBI among all hitters in MLB.
• Torkelson carries a three-game hitting streak into this matchup. In his last five games he is hitting .313 with a double, two home runs, four walks and five RBIs.
• Torres is hitting .284 to lead his team.
• Torres ranks 113th in homers and 63rd in RBI on the year.
• Riley Greene has nine doubles, 11 home runs and 13 walks while batting .276.
• Greene has at least one base hit in two straight games. During his last five outings he is hitting .400 with three doubles, two home runs, a walk and five RBIs.
• Kerry Carpenter's .284 batting average paces his team.

Tigers Team Props

Cardinals Recent Betting Performance

• The Cardinals have played as underdogs in six of their past 10 games and have gone 5-1 in those contests.
• In their last 10 games with a total, the Cardinals and their opponents are 4-6-0 when it comes to hitting the over.
• The Cardinals are 8-2-0 ATS over their last 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Lars Nootbaar has swatted a team-leading seven home runs.
• Nootbaar's home run total places him 62nd in the big leagues, and he is 50th in RBI.
• Brendan Donovan has a club-leading .337 batting average.
• Donovan is currently 175th in home runs and 82nd in RBI in the major leagues.
• Nolan Arenado is batting .241 with 10 doubles, four home runs and 17 walks.
• Willson Contreras has collected a team-leading 27 runs batted in.

Cardinals Team Props

Tigers vs. Cardinals Highlights | MLB on FOX

Check out the top moments from this MLB game between the Detroit Tigers and the St. Louis Cardinals!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox? Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

St. Louis Cardinals

Detroit Tigers