Reds vs. Twins Prediction, Odds, Picks - June 17

Elly De La Cruz and the Cincinnati Reds square off against Byron Buxton and the Minnesota Twins on Tuesday at 7:10 p.m. ET in the first game of a three-game series. The favored Reds have -132 moneyline odds to win against the underdog Twins, who are listed at +110. Cincinnati is the favorite on the run line (-1.5). The total is 8.5 runs for the contest.

Check out everything you need from a betting perspective on the Reds-Twins game, regarding the run line, moneyline and total, plus expert picks.

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Reds vs. Tigers Highlights | MLB on FOX

Check out the best moments between the Cincinnati Reds and Detroit Tigers.

Reds vs. Twins Game Information & Odds

• When: Tuesday, June 17, 2025 at 7:10 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and MNNT

Reds vs. Twins Prediction

• Score Prediction: Reds 4, Twins 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Reds 54%, Twins 46%

Reds vs. Twins Betting Insights

• The Reds have entered the game as favorites 30 times this season and won 14, or 46.7%, of those games.
• Cincinnati has a record of 8-7 in games when oddsmakers favor them by at least -132 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Reds have a 56.9% chance to win.
• The Twins have been victorious in 10, or 43.5%, of the 23 contests they have been chosen as underdogs in this season.
• This season, Minnesota has come away with a win three times in eight chances when named as an underdog of at least +110 or worse on the moneyline.
• The moneyline set for this matchup implies the Twins have a 47.6% chance of walking away with the win.

Reds Recent Betting Performance

• The Reds were the moneyline favorite for three of their last 10 games, and they finished 1-2 in those matchups.
• In their last 10 matchups -- all had a set run total -- the Reds and their opponents combined to go over the total seven times.
• The Reds' record against the spread is 6-4-0 over their past 10 games.

Reds Recent Stats

Reds Player Insights

• De La Cruz has gone yard 16 times in the 2025 campaign while knocking in 50 runs, both totals that lead the Reds.
• De La Cruz's home runs put him 13th in MLB, and he is 10th in RBI.
• De La Cruz carries a six-game hitting streak into this matchup. During his last 10 outings he is hitting .361 with three doubles, four home runs, six walks and seven RBIs.
• TJ Friedl's .290 batting average paces his team.
• Friedl ranks 95th in homers and 125th in RBI in the major leagues.
• Gavin Lux is hitting .281 with 14 doubles, a triple, two home runs and 28 walks.
• Lux will look to build on his two-game hitting in this matchup. In his last five games he is batting .316 with a walk and three RBIs.
• Jose Trevino is batting .295 with 15 doubles, four home runs and nine walks.

Reds Team Props

Twins Recent Betting Performance

• Over the past 10 games, the Twins have been underdogs just once and lost that contest.
• In their last 10 games with a total, the Twins and their opponents have combined to hit the over seven times.
• The Twins have won four of their last 10 games against the spread.

Twins Recent Stats

Twins Player Insights

• Buxton leads the lineup with a batting average of .273, while leading the Twins in home runs, with 11 and runs batted in with 41.
• Among all hitters in MLB, Buxton's home run total is 44th and his RBI tally is 32nd.
• Trevor Larnach has nine doubles, a triple, 10 home runs and 23 walks while hitting .254.
• Larnach ranks 59th overall in home runs and 84th in RBI this year.
• Ty France has 11 doubles, five home runs and 12 walks while batting .269.
• Willi Castro has 11 doubles, a triple, seven home runs and 17 walks while batting .290.

Twins Team Props

Reds vs. Tigers Highlights | MLB on FOX

Check out the best moments between the Cincinnati Reds and Detroit Tigers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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