Reds vs. Padres Prediction, Odds, Picks - June 28

Fernando Tatis Jr. and the San Diego Padres will hit the field against the Cincinnati Reds and starter Andrew Abbott on Saturday. First pitch is at 4:10 p.m. ET at Great American Ball Park. The Padres are +129 moneyline underdogs for this matchup with the favorite Reds (-154). Cincinnati is a 1.5-run favorite (at +132 odds). The total is 9.5 runs for this contest (with -106 odds on the over and -115 odds to go under).

Here is everything you need to know from a betting perspective on the Reds-Padres game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Reds Highlights | MLB on FOX

Check out the best highlights between the San Diego Padres and Cincinnati Reds.

Reds vs. Padres Game Information & Odds

• When: Saturday, June 28, 2025 at 4:10 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and SDPA

Reds vs. Padres Prediction

• Score Prediction: Reds 4, Padres 3
• Total Prediction: Under 9.5 runs
• Win Probabilities: Reds 54%, Padres 46%

Reds vs. Padres Betting Insights

• The Reds have won 17, or 50%, of the 34 games they've played as favorites this season.
• This season Cincinnati has won six of its nine games, or 66.7%, when favored by at least -154 on the moneyline.
• The oddsmakers' moneyline implies a 60.6% chance of a victory for the Reds.
• The Padres have won in 18, or 47.4%, of the 38 contests they have been named as odds-on underdogs this year.
• This year, San Diego has won seven of 17 games when listed as at least +129 or worse on the moneyline.
• The moneyline set for this matchup implies the Padres have a 43.7% chance of walking away with the win.

Reds Recent Betting Performance

• The Reds were favored on the moneyline for four of their last 10 games, and they went 3-1 in those matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Reds and their opponents combined to go over the run total three times.
• The Reds have a 6-4-0 record against the spread over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz leads the Reds in home runs (18) and runs batted in (56).
• In all of Major League Baseball, De La Cruz is 13th in homers and 12th in RBI.
• De La Cruz has collected a hit in seven straight games. In his last 10 games he is hitting .325 with a double, two triples, two home runs, two walks and six RBIs.
• TJ Friedl's .284 batting average paces his team.
• Friedl ranks 129th in homers and 130th in RBI among all MLB batters this year.
• Spencer Steer is batting .250 with 13 doubles, a triple, nine home runs and 20 walks.
• Steer has at least one base hit in six straight games. During his last 10 outings he is hitting .410 with three doubles, a triple, four home runs and nine RBIs.
• Gavin Lux is hitting .266 with 14 doubles, a triple, four home runs and 32 walks.
• Lux is riding a three-game hitting streak into this one. During his last five outings he is batting .200 with a home run, a walk and five RBIs.

Reds Team Props

Padres Recent Betting Performance

• The Padres have played as underdogs in three of their past 10 games and won one of those contests.
• The Padres and their opponents have combined to hit the over three times in their last 10 games with a total.
• The Padres have four wins against the spread in their last 10 chances.

Padres Recent Stats

Padres Player Insights

• Manny Machado leads the Padres with 47 runs batted in while accumulating a team-high batting average of .295.
• Machado's home run total places him 39th in MLB, and he ranks 31st in RBI.
• Tatis has shown off his power as he leads his team with 15 home runs.
• Tatis ranks 27th overall in home runs and 83rd in RBI this year.
• Luis Arraez is batting .284 with 16 doubles, four triples, three home runs and 13 walks.
• Gavin Sheets is hitting .259 with 12 doubles, a triple, 12 home runs and 22 walks.

Padres Team Props

Padres vs. Reds Highlights | MLB on FOX

Check out the best highlights between the San Diego Padres and Cincinnati Reds.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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