Phillies vs. Twins Prediction, Odds, Picks - September 27

Alec Bohm and the Philadelphia Phillies will see Mick Abel on the mound for the Minnesota Twins in the second game of a three-game series, Saturday at 6:05 p.m. ET. The Twins are +192 moneyline underdogs in this matchup with the Phillies (-235). Philadelphia is favored on the run line (-1.5). The over/under is 8.5 runs for this matchup.

Check out everything you need to know from a betting perspective on the Phillies-Twins game, regarding the run line, moneyline and total, plus expert picks.

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Phillies vs. Twins Game Information & Odds

• When: Saturday, September 27, 2025 at 6:05 p.m. ET
• Where: Citizens Bank Park in Philadelphia, Pennsylvania
• How to watch on TV: NBCS-PH and MNNT

Phillies vs. Twins Prediction

• Score Prediction: Phillies 5, Twins 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Phillies 60%, Twins 40%

Phillies vs. Twins Betting Insights

• This season, the Phillies have won 79 out of the 127 games, or 62.2%, in which they've been favored.
• Philadelphia is 14-2 this season when entering a game favored by -235 or more on the moneyline.
• The Phillies have a 70.1% chance to win this game based on the implied probability of the moneyline.
• The Twins have won in 27, or 39.1%, of the 69 contests they have been named as odds-on underdogs this year.
• Minnesota has been listed as an underdog of +192 or more on two occasions this season and lost both games.
• Sportsbooks have implied with the moneyline set for this matchup that the Twins have a 34.2% chance of pulling out a win.

Phillies Recent Betting Performance

• The Phillies have a 3-2 record across the five games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings, the Phillies and their opponents combined to go over the total six times (all 10 games had set totals).
• The Phillies are 4-6-0 against the spread over their past 10 games.

Phillies Recent Stats

Phillies Player Insights

• Kyle Schwarber paces the Phillies in home runs (56) and runs batted in (132).
• Among all hitters in MLB, Schwarber's home run total ranks him second, and his RBI tally puts him first.
• Bryce Harper has 32 doubles, 27 home runs and 69 walks while batting .263.
• Harper is 37th in homers and 66th in RBI in the bigs.
• Harper heads into this matchup looking for his fourth game in a row with a hit. In his last five games he is hitting .263 with three walks.
• Bryson Stott is hitting .256 with 22 doubles, three triples, 13 home runs and 54 walks.
• Nick Castellanos has 27 doubles, two triples, 17 home runs and 32 walks while batting .252.

Phillies Team Props

Twins Recent Betting Performance

• The Twins have played as underdogs in nine of their past 10 games and won three of those contests.
• When it comes to hitting the over, the Twins and their opponents are 2-7-1 in their last 10 games with a total.
• The Twins have four wins against the spread in their last 10 chances.

Twins Recent Stats

Twins Player Insights

• Byron Buxton paces the Twins with 34 home runs and 82 runs batted in, while recording a team-best batting average of .263.
• Among all hitters in the majors, Buxton ranks 13th in homers and 49th in RBI.
• Trevor Larnach is hitting .249 with 23 doubles, a triple, 17 home runs and 53 walks.
• Larnach is 111th among all hitters in MLB in home runs, and 129th in RBI.
• Brooks Lee is batting .235 with 15 doubles, a triple, 16 home runs and 30 walks.
• Ryan Jeffers has 24 doubles, nine home runs and 49 walks while batting .259.

Twins Team Props

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