Padres vs. Rockies Prediction, Odds, Picks - September 6

The San Diego Padres and Jake Cronenworth will hit the field against the Colorado Rockies and Mickey Moniak on Saturday at 8:10 p.m. ET, in the second game of a three-game series at Coors Field. The favored Padres have -236 moneyline odds to win against the underdog Rockies, who are listed at +194. San Diego is favored on the run line (-1.5). The matchup's total has been set at 11.5 runs.

Here is everything you need to know from a betting perspective on the Padres-Rockies game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Rockies Highlights | MLB on FOX

Check out the best highlights between the San Diego Padres and Colorado Rockies.

Padres vs. Rockies Game Information & Odds

• When: Saturday, September 6, 2025 at 8:10 p.m. ET
• Where: Coors Field in Denver, Colorado
• How to watch on TV: COLR and SDPA

Padres vs. Rockies Prediction

• Score Prediction: Padres 5, Rockies 4
• Total Prediction: Under 11.5 runs
• Win Probabilities: Padres 57%, Rockies 43%

Padres vs. Rockies Betting Insights

• This season, the Padres have won 44 out of the 76 games, or 57.9%, in which they've been favored.
• San Diego has a record of 2-1 in games when sportsbooks favor them by at least -236 on the moneyline.
• The sportsbooks' moneyline implies a 70.2% chance of a victory for the Padres.
• The Rockies have been victorious in 39, or 28.5%, of the 137 contests they have been chosen as underdogs in this season.
• Colorado has a win-loss record of 14-49 when favored by +194 or worse by oddsmakers this year.
• Oddsmakers have implied with the moneyline set for this matchup that the Rockies have a 34% chance of pulling out a win.

Padres Recent Betting Performance

• The Padres were favored on the moneyline in six of their last 10 games, and they finished 1-5 in those matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Padres and their opponents combined to hit the over six times.
• The Padres have put together a 2-8-0 record against the spread over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Fernando Tatis Jr. is hitting .261 with 27 doubles, two triples, 19 home runs and 82 walks.
• Including all MLB hitters, Tatis ranks 71st in batting average, 14th in on-base percentage, and 79th in slugging.
• Tatis has collected a hit in two games in a row. During his last five outings he is batting .158 with a home run, three walks and an RBI.
• Manny Machado has hit 22 home runs with 81 RBI. Both are team-highs.
• Machado ranks 49th in homers and 24th in RBI among all MLB batters this year.
• Luis Arraez paces the Padres with a .284 batting average.
• Ramon Laureano's 22 home runs lead his team.
• Laureano takes a six-game streak with at least one hit into this one. In his last 10 outings he is batting .316 with two doubles, three home runs, two walks and nine RBIs.

Padres Team Props

Rockies Recent Betting Performance

• The Rockies have played as underdogs in 10 of their past 10 games and have gone 3-7 in those contests.
• In their last 10 games with a total, the Rockies and their opponents have combined to hit the over three times.
• Over their last 10 games, the Rockies are 5-5-0 against the spread.

Rockies Recent Stats

Rockies Player Insights

• Hunter Goodman leads the squad with a batting average of .285, and paces the Rockies in home runs, with 28 and runs batted in with 85.
• In all of MLB, Goodman ranks 18th in home runs and 21st in RBI.
• Goodman has collected a hit in three straight games. During his last five outings he is hitting .526 with two doubles, two home runs, a walk and 10 RBIs.
• Moniak is hitting .266 with 17 doubles, eight triples, 18 home runs and 20 walks.
• Moniak is 84th in home runs and 117th in RBI among all major league hitters this season.
• Jordan Beck is batting .269 with 25 doubles, five triples, 14 home runs and 39 walks.
• Brenton Doyle is hitting .247 with 19 doubles, two triples, 14 home runs and 29 walks.

Rockies Team Props

Padres vs. Rockies Highlights | MLB on FOX

Check out the best highlights between the San Diego Padres and Colorado Rockies.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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