Padres vs. Pirates Prediction, Odds, Picks - May 30

The San Diego Padres and Pittsburgh Pirates will send Nick Pivetta and Mitch Keller, respectively, to the mound when the two clubs play on Friday at PETCO Park, at 9:40 p.m. ET. The favored Padres have -187 moneyline odds to win against the underdog Pirates, who are listed at +156. San Diego (-1.5) is the favorite on the run line. The over/under is 7.5 runs for the contest (with -101 odds to go over and -119 odds to go under).

Here is everything you need to know from a betting perspective on the Padres-Pirates game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Pirates Game Information & Odds

• When: Friday, May 30, 2025 at 9:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: MLB Network, SDPA, and SportsNet PT

Padres vs. Pirates Prediction

• Score Prediction: Padres 4, Pirates 3
• Total Prediction: Under 7.5 runs
• Win Probabilities: Padres 57%, Pirates 43%

Padres vs. Pirates Betting Insights

• This season, the Padres have been favored 31 times and won 19, or 61.3%, of those games.
• San Diego has a record of 7-3, a 70% win rate, when favored by -187 or more by oddsmakers this season.
• Oddsmakers have implied with the moneyline set for this matchup that the Padres have a 65.2% chance to win.
• The Pirates have been chosen as underdogs in 40 games this year and have walked away with the win 15 times (37.5%) in those games.
• This year, Pittsburgh has won four of 10 games when listed as at least +156 or worse on the moneyline.
• The moneyline set for this matchup implies the Pirates have a 39.1% chance of coming away with a victory in the contest.

Padres Recent Betting Performance

• The Padres were the moneyline favorite in six of their last 10 games, and they finished 2-4 in those matchups.
• In their last 10 matchups (all had set totals), the Padres combined with their opponents to go over the run total four times.
• The Padres have gone 3-7-0 against the spread over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Fernando Tatis Jr. has hit a team-best 13 home runs.
• Among all hitters in baseball, Tatis is 12th in homers and 67th in RBI.
• Manny Machado's .313 batting average leads his team.
• Machado is 101st in homers and 85th in RBI on the year.
• Machado has six games in a row with at least one hit. In his last 10 outings he is batting .275 with two doubles, three home runs, four walks and five RBIs.
• Luis Arraez is batting .290 with nine doubles, three triples, three home runs and 10 walks.
• Arraez has at least one base hit in two games in a row. In his last five games he is hitting .211 with a double, a walk and three RBIs.
• Gavin Sheets' 34 runs batted in are a team-high mark.

Padres Team Props

Pirates Recent Betting Performance

• The Pirates have played as underdogs in nine of their past 10 games and won five of those contests.
• When it comes to hitting the over, the Pirates and their opponents are 5-4-1 in their last 10 games with a total.
• The Pirates have a record of 6-4-0 ATS over their last 10 games.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz has put up a team-best 12 home runs.
• In all of the big leagues, Cruz ranks 15th in home runs and 79th in RBI.
• Bryan Reynolds has made the most of his opportunities as he leads his team with 31 runs batted in.
• Reynolds is currently 80th in homers and 37th in RBI in the big leagues.
• Isiah Kiner-Falefa has eight doubles, a triple, a home run and nine walks while batting .297.
• Andrew McCutchen is hitting .253 with eight doubles, three home runs and 26 walks.

Pirates Team Props

Padres' Fernando Tatis Jr. hits walk-off home run vs. Angels

Fernando Tatis Jr. launched a walk-off home run in the San Diego Padres' 6-4 lead over the Los Angeles Angels.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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