Padres vs. Angels Prediction, Odds, Picks - May 12

Manny Machado and the San Diego Padres will hit the field at PETCO Park against the Los Angeles Angels and Nolan Schanuel on Monday. The Padres are the favorite in this one, at -223, while the underdog Angels have +185 odds to upset. San Diego (-1.5) is the favorite on the run line. The contest's over/under is set at 7 runs.

Here's everything you need from a betting perspective on the Padres-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Angels Game Information & Odds

• When: Monday, May 12, 2025 at 9:40 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: SDPA and FDSW

Padres vs. Angels Prediction

• Score Prediction: Padres 5, Angels 3
• Total Prediction: Over 7 runs
• Win Probabilities: Padres 62%, Angels 38%

Padres vs. Angels Betting Insights

• The Padres have been favorites in 20 games this season and won 15 (75%) of those contests.
• This season San Diego has won two of its three games when favored by at least -223 on the moneyline.
• The Padres have a 69% chance to win this game based on the implied probability of the moneyline.
• The Angels have been chosen as underdogs in 31 games this year and have walked away with the win 12 times (38.7%) in those games.
• This will be the worst odds to win that sportsbooks have assigned Los Angeles this season with a +185 moneyline set for this game.
• The Angels have an implied victory probability of 35.1% according to the moneyline set for this matchup.

Padres Recent Betting Performance

• The Padres went 4-1 across the five games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups (all had set totals), the Padres combined with their opponents to hit the over on the run total six times.
• The Padres have put together an 8-2-0 record against the spread over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Fernando Tatis Jr. is the Padres best power hitter, connecting on nine home runs this season in addition to delivering 23 RBI, both team highs.
• Tatis is 14th in homers and 39th in RBI among all hitters in baseball.
• Tatis carries a five-game hitting streak into this matchup. During his last five outings he is batting .333 with a double, a home run, two walks and five RBIs.
• Manny Machado has a club-leading .324 batting average.
• Machado is 152nd in homers and 67th in RBI in the majors.
• Machado has 11 games in a row with at least one hit. During his last 10 outings he is batting .447 with four doubles, a home run, five walks and eight RBIs.
• Luis Arraez has four doubles, two triples, three home runs and eight walks while batting .289.
• Xander Bogaerts is hitting .244 with nine doubles, two home runs and 18 walks.

Padres Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in 10 of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Angels and their opponents are 7-3-0 when it comes to hitting the over.
• The Angels are 4-6-0 ATS over their last 10 games.

Angels Recent Stats

Angels Player Insights

• Nolan Schanuel is batting .258 with six doubles, a triple, two home runs and 16 walks, while getting on base at a rate of .342.
• Among all hitters in the big leagues, Schanuel's home run total ranks 200th and his RBI tally ranks 239th.
• Joseph Ward has six doubles, eight home runs and nine walks while hitting .182.
• Ward is 30th overall in home runs and 105th in RBI this year.
• Jorge Soler has eight doubles, six home runs and 11 walks while hitting .226.
• Logan O'Hoppe paces the Angels in home runs (nine), runs batted in (18) and has posted a team-best batting average of .264.

Angels Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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