Orioles vs. Giants Prediction, Odds, Picks - August 29

The San Francisco Giants and Rafael Devers hit the field at Oracle Park against Jackson Holliday and the Baltimore Orioles on Friday. The Orioles are the favorite in this one, at -124, while the underdog Giants have +106 odds to win. Baltimore (-1.5) is favored on the run line. A 7.5-run total has been set for the matchup.

Take a look at everything you need to know from a betting perspective on the Orioles-Giants game, regarding the run line, moneyline and total, plus expert picks.

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Red Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Baltimore Orioles.

Orioles vs. Giants Game Information & Odds

• When: Friday, August 29, 2025 at 10:15 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to watch on TV: Apple TV+

Orioles vs. Giants Prediction

• Score Prediction: Giants 4, Orioles 3
• Total Prediction: Under 7.5 runs
• Win Probabilities: Orioles 55%, Giants 45%

Orioles vs. Giants Betting Insights

• The Orioles have won 28, or 45.9%, of the 61 games they've played as favorites this season.
• Baltimore has entered 39 games this season favored by -124 or more and is 20-19 in those contests.
• The implied probability of a win from the Orioles, based on the moneyline, is 55.4%.
• The Giants have been victorious in 27, or 48.2%, of the 56 contests they have been chosen as underdogs in this season.
• San Francisco has a win-loss record of 19-21 when favored by +106 or worse by bookmakers this year.
• The moneyline set for this matchup implies the Giants have a 48.5% chance of coming away with a victory in the contest.

Orioles Recent Betting Performance

• The Orioles were the moneyline favorite for three of their last 10 games, and they finished 1-2 in those matchups.
• Over their last 10 outings (all had set totals), the Orioles combined with their opponents to go over the total four times.
• The Orioles' ATS record is 5-5-0 over their past 10 games.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson's 16 round-trippers and 59 RBI both lead the Orioles, on top of his team-high .277 average.
• Among all MLB hitters, Henderson is 33rd in batting average, 43rd in on-base percentage, and 49th in slugging.
• Holliday is hitting .242 with 18 doubles, two triples, 15 home runs and 38 walks.
• Holliday is 109th in homers and 137th in RBI in the major leagues.
• Colton Cowser is batting .219 with 11 doubles, 12 home runs and 17 walks.
• Ryan Mountcastle has 14 doubles, four home runs and 11 walks while batting .251.

Orioles Team Props

Giants Recent Betting Performance

• The Giants have played as underdogs in nine of their past 10 games and won five of those contests.
• The Giants and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Giants are 7-3-0 ATS over their last 10 games.

Giants Recent Stats

Giants Player Insights

• Devers paces the Giants with 27 long balls and runs batted in, driving in 89.
• In all of the majors, Devers ranks 16th in homers and 11th in RBI.
• Devers brings a hitting streak of three games into this game. In his last five games he is batting .438 with a double, two home runs, three walks and six RBIs.
• Jung Hoo Lee is batting .261 with 30 doubles, 10 triples, seven home runs and 41 walks.
• Lee is currently 238th in home runs and 144th in RBI in the big leagues.
• Willy Adames is batting .224 with 18 doubles, two triples, 24 home runs and 64 walks.
• Heliot Ramos leads the Giants with a team-high batting average of .265.

Giants Team Props

Red Sox vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Boston Red Sox and the Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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