Mariners vs. Cardinals Prediction, Odds, Picks - September 9

Cal Raleigh and the Seattle Mariners meet Alec Burleson and the St. Louis Cardinals on Tuesday at 9:40 p.m. ET in the second game of a three-game series. The Cardinals are +168 moneyline underdogs for this matchup with the favored Mariners (-204). Seattle is a 1.5-run favorite (at +105 odds). The total is 7.5 runs for this matchup.

Check out everything you need to know from a betting perspective on the Mariners-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Cardinals vs. Mariners Highlights | MLB on FOX

Check out the best moments between the St. Louis Cardinals and the Seattle Mariners.

Mariners vs. Cardinals Game Information & Odds

• When: Tuesday, September 9, 2025 at 9:40 p.m. ET
• Where: T-Mobile Park in Seattle, Washington
• How to watch on TV: ROOT Sports NW and FDSMW

Mariners vs. Cardinals Prediction

• Score Prediction: Mariners 5, Cardinals 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Mariners 55%, Cardinals 45%

Mariners vs. Cardinals Betting Insights

• The Mariners have been favorites in 99 games this season and won 54 (54.5%) of those contests.
• This season Seattle has won seven of its nine games, or 77.8%, when favored by at least -204 on the moneyline.
• The bookmakers' moneyline implies a 67.1% chance of a victory for the Mariners.
• The Cardinals have been victorious in 38, or 48.7%, of the 78 contests they have been chosen as underdogs in this season.
• This year, St. Louis has won one of seven games when listed as at least +168 or worse on the moneyline.
• The Cardinals have an implied victory probability of 37.3% according to the moneyline set by sportsbooks for this matchup.

Mariners Recent Betting Performance

• The Mariners were favored on the moneyline for seven of their last 10 games, and they finished 3-4 in those matchups.
• In their last 10 outings (all had set totals), the Mariners combined with their opponents to go over the total six times.
• The Mariners' ATS record is 4-6-0 over their past 10 games.

Mariners Recent Stats

Mariners Player Insights

• Raleigh leads the Mariners in home runs (53) and runs batted in (113).
• Raleigh's home runs rank him first in MLB, and he is second in RBI.
• Julio Rodriguez is batting .268 with 26 doubles, four triples, 30 home runs and 34 walks.
• Rodriguez is 12th in homers and 16th in RBI among all MLB hitters this year.
• Rodriguez enters this matchup looking for his fourth game in a row with a hit. In his last five games he is hitting .381 with two doubles, three home runs and 11 RBIs.
• Josh Naylor leads the Mariners with a .282 batting average.
• Naylor is on a three-game hitting streak entering this contest. In his last five games he is hitting .267 with a double, two home runs, a walk and six RBIs.
• Eugenio Suarez is batting .236 with 25 doubles, 45 home runs and 40 walks.

Mariners Team Props

Cardinals Recent Betting Performance

• The Cardinals have played as underdogs in six of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Cardinals and their opponents have combined to hit the over four times.
• The Cardinals have a record of 5-5-0 ATS over their last 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Burleson leads the team in batting average with a high-water mark of .286.
• In all of the majors, Burleson ranks 96th in homers and 92nd in RBI.
• Willson Contreras been a consistent power bat this season, as he paces his team with 20 home runs and 78 runs batted in.
• Contreras is 65th overall in homers and 36th in RBI this year.
• Masyn Winn is hitting .253 with 27 doubles, nine home runs and 34 walks.
• Lars Nootbaar is hitting .241 with 22 doubles, a triple, 13 home runs and 55 walks.

Cardinals Team Props

Cardinals vs. Mariners Highlights | MLB on FOX

Check out the best moments between the St. Louis Cardinals and the Seattle Mariners.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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