Guardians vs. Blue Jays Prediction, Odds, Picks - June 26

Jose Ramirez and the Cleveland Guardians will try to get to Kevin Gausman when he starts for the Toronto Blue Jays on Thursday at 1:10 p.m. ET. Bookmakers list the Guardians as -134 moneyline favorites, while giving the underdog Blue Jays +114 moneyline odds. Cleveland is favored on the run line (-1.5 with +163 odds). The over/under is 7.5 runs for this game.

Take a look at everything you need from a betting perspective on the Guardians-Blue Jays game, regarding the run line, moneyline and total, plus expert picks.

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Check out the best moments between the Toronto Blue Jays and Cleveland Guardians!

Guardians vs. Blue Jays Game Information & Odds

• When: Thursday, June 26, 2025 at 1:10 p.m. ET
• Where: Progressive Field in Cleveland, Ohio
• How to watch on TV: CLEG and SNET

Guardians vs. Blue Jays Prediction

• Score Prediction: Guardians 5, Blue Jays 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Guardians 52%, Blue Jays 48%

Guardians vs. Blue Jays Betting Insights

• This season, the Guardians have won 18 out of the 29 games, or 62.1%, in which they've been favored.
• Cleveland has entered 12 games this season favored by -134 or more and is 9-3 in those contests.
• The moneyline for this contest implies a 57.3% chance of a victory for the Guardians.
• The Blue Jays have been underdogs in 46 games this season and have come away with the win 23 times (50%) in those contests.
• This season, Toronto has come away with a win 10 times in 20 chances when named as an underdog of at least +114 or worse on the moneyline.
• Oddsmakers have implied with the moneyline set for this matchup that the Blue Jays have a 46.7% chance of pulling out a win.

Guardians Recent Betting Performance

• The Guardians have a 3-1 record from the four games they were moneyline favorites over their last 10 matchups.
• Over their last 10 outings, the Guardians and their opponents combined to hit the over two times (all 10 of the games had set totals).
• The Guardians have gone 6-4-0 against the spread over their past 10 games.

Guardians Recent Stats

Guardians Player Insights

• Ramirez has accumulated a team-best batting average of .318, while pacing the Guardians in home runs (13) and runs batted in (38).
• In all of MLB, Ramirez is 39th in home runs and 71st in RBI.
• Steven Kwan has 17 doubles, six home runs and 28 walks while hitting .307.
• Kwan ranks 168th in homers and 178th in RBI in the bigs.
• Carlos Santana has six doubles, nine home runs and 35 walks while hitting .237.
• Kyle Manzardo is batting .221 with 11 doubles, two triples, 12 home runs and 25 walks.
• Manzardo is riding a four-game hitting streak into this one. During his last five outings he is hitting .357 with a double, a home run, two walks and an RBI.

Guardians Team Props

Blue Jays Recent Betting Performance

• The Blue Jays have played as underdogs three times over their past 10 games and lost each of those contests.
• In their last 10 games with a total, the Blue Jays and their opponents have failed to hit the over five times.
• Over their last 10 games, the Blue Jays are 5-5-0 against the spread.

Blue Jays Recent Stats

Blue Jays Player Insights

• Vladimir Guerrero Jr. has launched a team-best 11 home runs.
• In all of the majors, Guerrero is 61st in homers and 60th in RBI.
• Bo Bichette been a consistent power bat this season, as he paces his team with 11 home runs and 48 RBI.
• Bichette is 61st overall in home runs and 27th in RBI this season.
• George Springer has 11 home runs, best in the lineup.
• Alejandro Kirk paces the Blue Jays with a .310 batting average.

Blue Jays Team Props

Blue Jays vs. Guardians Highlights | MLB on FOX

Check out the best moments between the Toronto Blue Jays and Cleveland Guardians!

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Cleveland Guardians

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