Giants vs. Diamondbacks Prediction, Odds, Picks - September 9

Robbie Ray will start for the San Francisco Giants on Tuesday at Oracle Park against Geraldo Perdomo and the Arizona Diamondbacks. First pitch is at 9:45 p.m. ET for the second game of a three-game series. Bookmakers list the Giants as -143 moneyline favorites, while giving the underdog Diamondbacks +120 moneyline odds. San Francisco is a 1.5-run favorite (at +155 odds). The total is 7.5 runs for the game.

Check out everything you need to know from a betting perspective on the Giants-Diamondbacks game, regarding the run line, moneyline and total, plus expert picks.

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Diamondbacks vs. Giants Highlights | MLB on FOX

Check out the best moments between Arizona Diamondbacks and the San Francisco Giants.

Giants vs. Diamondbacks Game Information & Odds

• When: Tuesday, September 9, 2025 at 9:45 p.m. ET
• Where: Oracle Park in San Francisco, California
• How to watch on TV: NBCS-BA and ARID

Giants vs. Diamondbacks Prediction

• Score Prediction: Giants 5, Diamondbacks 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Giants 54%, Diamondbacks 46%

Giants vs. Diamondbacks Betting Insights

• The Giants have won 45, or 53.6%, of the 84 games they've played as favorites this season.
• San Francisco has a record of 30-23 in games when bookmakers favor them by at least -143 on the moneyline.
• The Giants have a 58.8% chance to win this game based on the implied probability of the moneyline.
• The Diamondbacks have been chosen as underdogs in 60 games this year and have walked away with the win 29 times (48.3%) in those games.
• This year, Arizona has won 16 of 27 games when listed as at least +120 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Diamondbacks have a 45.5% chance of pulling out a win.

Giants Recent Betting Performance

• The Giants went 6-1 over the seven games they were a moneyline favorite in their last 10 matchups.
• In their last 10 outings (all had set totals), the Giants combined with their opponents to hit the over on the run total seven times.
• The Giants have an 8-2-0 record against the spread over their past 10 games.

Giants Recent Stats

Giants Player Insights

• Rafael Devers leads the Giants with 31 home runs and 100 runs batted in.
• Including all MLB hitters, Devers is 70th in batting average, ninth in on-base percentage, and 27th in slugging.
• Jung Hoo Lee has a club-leading .271 batting average.
• Lee ranks 224th in home runs and 144th in RBI in the bigs.
• Willy Adames is hitting .230 with 19 doubles, two triples, 27 home runs and 68 walks.
• Heliot Ramos is hitting .266 with 23 doubles, a triple, 17 home runs and 45 walks.

Giants Team Props

Diamondbacks Recent Betting Performance

• The Diamondbacks have played as underdogs in six of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Diamondbacks and their opponents have combined to hit the over four times.
• The Diamondbacks have seven wins against the spread in their last 10 chances.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Perdomo has driven in the most runs for the Diamondbacks with 91 runs batted in.
• Among all hitters in MLB, Perdomo is 96th in homers and 15th in RBI.
• Corbin Carroll has shown off his power as he leads his team with 30 home runs.
• Carroll ranks 12th among all hitters in MLB in home runs, and 48th in RBI.
• Ketel Marte has put up a team-high batting average of .287.
• Gabriel Moreno is batting .283 with 11 doubles, a triple, eight home runs and 18 walks.

Diamondbacks Team Props

Diamondbacks vs. Giants Highlights | MLB on FOX

Check out the best moments between Arizona Diamondbacks and the San Francisco Giants.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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San Francisco Giants

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