Dodgers vs. Padres Prediction, Odds, Picks - August 16

Mookie Betts and the Los Angeles Dodgers take on the San Diego Padres and starter Dylan Cease on Saturday at 9:10 p.m. ET at Dodger Stadium. The Padres are +130 moneyline underdogs in this matchup against the favored Dodgers (-156). Los Angeles is favored on the run line (-1.5 with +134 odds). An 8.5-run over/under is set for the game.

Take a look at everything you need to know from a betting perspective on the Dodgers-Padres game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Giants Highlights | MLB on FOX

Check out the best moments between the San Diego Padres and the San Francisco Giants.

Dodgers vs. Padres Game Information & Odds

• When: Saturday, August 16, 2025 at 9:10 p.m. ET
• Where: Dodger Stadium in Los Angeles, California
• How to watch on TV: SportsNet LA and SDPA

Dodgers vs. Padres Prediction

• Score Prediction: Dodgers 5, Padres 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Dodgers 54%, Padres 46%

Dodgers vs. Padres Betting Insights

• The Dodgers have been favorites in 106 games this season and won 62 (58.5%) of those contests.
• Los Angeles has entered 75 games this season favored by -156 or more and is 43-32 in those contests.
• The oddsmakers' moneyline implies a 60.9% chance of a victory for the Dodgers.
• The Padres have been victorious in 29, or 51.8%, of the 56 contests they have been chosen as underdogs in this season.
• San Diego has a win-loss record of 8-13 when favored by +130 or worse by sportsbooks this year.
• The Padres have an implied victory probability of 43.5% according to the moneyline set for this matchup.

Dodgers Recent Betting Performance

• The Dodgers went 4-6 across the 10 games they were favored on the moneyline in their last 10 matchups.
• Over their last 10 outings (all had set totals), the Dodgers combined with their opponents to go over the total six times.
• The Dodgers' ATS record is 3-7-0 over their past 10 games.

Dodgers Recent Stats

Dodgers Player Insights

• Shohei Ohtani is the Dodgers best power option, connecting on 43 long balls this season in addition to accumulating 80 RBI, both team highs.
• In all of the majors, Ohtani ranks second in homers and 13th in RBI.
• Mookie Betts has 17 doubles, a triple, 12 home runs and 44 walks while hitting .243.
• Betts ranks 128th in homers and 74th in RBI among all major league hitters this year.
• Freddie Freeman has 29 doubles, a triple, 14 home runs and 46 walks while hitting .301.
• Andy Pages is batting .277 with 20 doubles, a triple, 19 home runs and 24 walks.

Dodgers Team Props

Padres Recent Betting Performance

• The Padres have played as underdogs in three of their past 10 games and won two of those contests.
• The Padres and their opponents have combined to hit the over five times in their last 10 games with a total.
• The Padres are 6-4-0 ATS over their last 10 games.

Padres Recent Stats

Padres Player Insights

• Manny Machado leads the Padres with 20 home runs and 72 runs batted in, while recording a team-high batting average of .294.
• In all of the majors, Machado ranks 42nd in homers and 21st in RBI.
• Fernando Tatis Jr. is batting .264 with 21 doubles, two triples, 17 home runs and 70 walks.
• Tatis is 68th in home runs and 109th in RBI among all major league hitters this season.
• Luis Arraez is batting .288 with 23 doubles, four triples, six home runs and 25 walks.
• Xander Bogaerts has 27 doubles, 10 home runs and 47 walks while hitting .265.

Padres Team Props

Padres vs. Giants Highlights | MLB on FOX

Check out the best moments between the San Diego Padres and the San Francisco Giants.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Los Angeles Dodgers

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