Dodgers vs. Orioles Prediction, Odds, Picks - September 6

Jackson Holliday and the Baltimore Orioles take the field on Saturday at Oriole Park at Camden Yards against Yoshinobu Yamamoto, who is the named starter for the Los Angeles Dodgers. First pitch is set for 7:05 p.m. ET. The favored Dodgers have -143 moneyline odds to win against the underdog Orioles, who are listed at +120. Los Angeles is the run-line favorite (-1.5). The game's over/under is set at 7.5 runs.

Here is everything you need to know from a betting perspective on the Dodgers-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Dodgers vs Orioles Highlights | MLB on FOX

Check out the best highlights between the Los Angeles Dodgers and the Baltimore Orioles.

Dodgers vs. Orioles Game Information & Odds

• When: Saturday, September 6, 2025 at 7:05 p.m. ET
• Where: Oriole Park at Camden Yards in Baltimore, Maryland
• How to watch on TV: MASN and SportsNet LA

Dodgers vs. Orioles Prediction

• Score Prediction: Dodgers 5, Orioles 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Dodgers 51%, Orioles 49%

Dodgers vs. Orioles Betting Insights

• The Dodgers have been favorites in 124 games this season and won 70 (56.5%) of those contests.
• Los Angeles is 55-42 this season when entering a game favored by -143 or more on the moneyline.
• The implied probability of a win from the Dodgers, based on the moneyline, is 58.8%.
• The Orioles have been victorious in 36, or 46.2%, of the 78 contests they have been chosen as underdogs in this season.
• This season, Baltimore has come away with a win 14 times in 32 chances when named as an underdog of at least +120 or longer on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Orioles have a 45.5% chance of pulling out a win.

Dodgers Recent Betting Performance

• The Dodgers went 4-6 across the 10 games they were a moneyline favorite in their last 10 matchups.
• In their last 10 outings, the Dodgers and their opponents combined to hit the over on the run total two times (all 10 games had set totals).
• The Dodgers' record against the spread is 3-7-0 over their past 10 games.

Dodgers Recent Stats

Dodgers Player Insights

• The Dodgers' best power option comes in the form of Shohei Ohtani and his 46-dinger 87-RBI season, both team highs.
• In all of the majors, Ohtani ranks third in homers and 18th in RBI.
• Mookie Betts is hitting .250 with 19 doubles, a triple, 15 home runs and 54 walks.
• Betts is 118th in home runs and 91st in RBI on the season.
• Betts carries a two-game streak with at least one hit into this contest. During his last five outings he is hitting .300 with a double, a home run, a walk and two RBIs.
• Freddie Freeman paces the Dodgers with a team-high batting average of .296.
• Andy Pages has 22 doubles, a triple, 24 home runs and 27 walks while hitting .272.
• Pages is riding a two-game hitting streak into this one. During his last five outings he is hitting .200 with a home run and four RBIs.

Dodgers Team Props

Orioles Recent Betting Performance

• The Orioles have played as underdogs in nine of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Orioles and their opponents have combined to hit the over four times.
• The Orioles have seven wins against the spread in their last 10 chances.

Orioles Recent Stats

Orioles Player Insights

• Gunnar Henderson leads the Orioles with 16 home runs and 61 runs batted in, while recording a team-high batting average of .276.
• In all of MLB, Henderson ranks 102nd in home runs and 91st in RBI.
• Holliday's 16 home runs pace his team.
• Holliday ranks 102nd in homers and 133rd in RBI among all MLB hitters this season.
• Ryan Mountcastle has 18 doubles, five home runs and 13 walks while batting .266.
• Colton Cowser is hitting .211 with 12 doubles, 13 home runs and 17 walks.

Orioles Team Props

Dodgers vs Orioles Highlights | MLB on FOX

Check out the best highlights between the Los Angeles Dodgers and the Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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