Diamondbacks vs. Nationals Prediction, Odds, Picks - April 6

The Arizona Diamondbacks and Washington Nationals will meet on Sunday at Nationals Park, at 1:35 p.m. ET. Trevor Williams will start for Washington, aiming to shut down Josh Naylor and company. Bookmakers list the Diamondbacks as -181 moneyline favorites, while giving the underdog Nationals +151 moneyline odds to win. Arizona is the favorite on the run line (-1.5 with -108 odds). The game's over/under has been listed at 7.5 runs.

Check out everything you need to know from a betting perspective on the Diamondbacks-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Diamondbacks vs. Nationals Game Information & Odds

• When: Sunday, April 6, 2025 at 1:35 p.m. ET
• Where: Nationals Park in Washington D.C.
• How to watch on TV: MASN2 and ARID

Diamondbacks vs. Nationals Prediction

• Score Prediction: Diamondbacks 6, Nationals 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Diamondbacks 57%, Nationals 43%

Diamondbacks vs. Nationals Betting Insights

• This season, the Diamondbacks have won four out of the seven games in which they've been favored.
• Arizona has not entered a game this season as bigger favorites on the moneyline than the -181 odds on them winning this game.
• Bookmakers have implied with the moneyline set for this matchup that the Diamondbacks have a 64.4% chance to win.
• The Nationals have been underdogs in seven games this season and have come away with the win two times (28.6%) in those contests.
• Oddsmakers have given Washington the worst odds of winning it has seen this season with a +151 moneyline listed for this contest.
• The Nationals have an implied victory probability of 39.8% according to the moneyline set by sportsbooks for this matchup.

Diamondbacks Player Insights

• Eugenio Suarez has gone yard five times in the 2025 campaign while driving in 11 runs, both totals that lead the Diamondbacks.
• Suarez ranks second in home runs and fourth in RBI among all batters in baseball.
• Geraldo Perdomo has totaled 11 runs batted in to lead his team.
• Perdomo ranks 75th in homers and fourth in RBI in the bigs.
• Corbin Carroll is batting .235 with two doubles, three home runs and five walks.
• Naylor is batting .273 with three doubles and five walks.

Diamondbacks Team Props

Nationals Player Insights

• Keibert Ruiz leads the team in batting average with a mark of .320.
• Among all batters in the majors, Ruiz's home run total is 37th and his RBI tally ranks 57th.
• C.J. Abrams has put his power on display as he paces his team with three home runs.
• Abrams is currently 14th in home runs and 57th in RBI in the big leagues.
• Nate Lowe has been solid source of run production for the Nationals with three long balls and seven runs batted in.
• Amed Rosario is hitting .417 with a double and a home run.

Nationals Team Props

Diamondbacks vs. Yankees Highlights | MLB on FOX

Check out the best highlights between the Arizona Diamondbacks and the New York Yankees.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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