Diamondbacks vs. Cubs Prediction, Odds, Picks - April 18

Updated Apr. 18, 2025 2:00 p.m. ET

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Corbin Carroll and Kyle Tucker will be among the star attractions when the Arizona Diamondbacks play the Chicago Cubs on Friday at 2:20 p.m. ET, at Wrigley Field. The Diamondbacks are -114 moneyline favorites in this matchup against the Cubs (-105). Arizona is a 1.5-run favorite (at +133 odds). The over/under is 11.5 runs for the contest (with -105 odds on the over and -115 odds to go under).

Take a look at everything you need from a betting perspective on the Diamondbacks-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Diamondbacks vs. Cubs Game Information & Odds

• When: Friday, April 18, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and ARID

Diamondbacks vs. Cubs Prediction

• Score Prediction: Cubs 4, Diamondbacks 3
• Total Prediction: Under 11.5 runs
• Win Probabilities: Diamondbacks 56%, Cubs 44%

Diamondbacks vs. Cubs Betting Insights

• This season, the Diamondbacks have been favored 16 times and won 10, or 62.5%, of those games.
• This season Arizona has won 10 of its 16 games, or 62.5%, when favored by at least -114 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Diamondbacks have a 53.3% chance to win.
• The Cubs have been chosen as underdogs in 12 games this year and have walked away with the win five times (41.7%) in those games.
• Chicago has a win-loss record of 5-5 when favored by -105 or worse by oddsmakers this year.
• The Cubs have an implied victory probability of 51.2% according to the moneyline set by oddsmakers for this matchup.

FINAL

AZ 11 · CHC 13

MLB

RUN LINE

TO WIN

TOTAL

Arizona Diamondbacks

AZ

-1.5

-114

O 11.5

Chicago Cubs

CHC

+1.5

-105

U 11.5

Diamondbacks Recent Betting Performance

• The Diamondbacks went 6-3 over the nine games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings, the Diamondbacks and their opponents combined to hit the over three times (all 10 of the games had set totals).
• The Diamondbacks have gone 6-4-0 against the spread over their past 10 games.

Diamondbacks Recent Stats

Diamondbacks Player Insights

• Carroll has a team-high six homers.
• Including all MLB batters, Carroll ranks 13th in batting average, 20th in on-base percentage, and fifth in slugging.
• Carroll has collected a hit in 10 straight games. In his last 10 games he is hitting .386 with five doubles, a triple, three home runs, two walks and 11 RBI.
• Josh Naylor is hitting .324 to pace his team.
• Naylor ranks 28th in homers and 23rd in RBI among all hitters in baseball.
• Naylor enters this matchup looking for his sixth game in a row with a hit. In his last five games he is hitting .333 with a double, three home runs, three walks and four RBI.
• Geraldo Perdomo has racked up a team-high 18 runs batted in.
• Perdomo is on a three-game hitting streak entering this contest. During his last five outings he is batting .267 with a home run, eight walks and five RBI.
• Pavin Smith is batting .404 with seven doubles, three home runs and eight walks.
• Smith takes a four-game streak with at least one hit into this one. In his last five games he is batting .438 with two doubles, two home runs, three walks and three RBI.

Diamondbacks Team Props

Cubs Recent Betting Performance

• The Cubs have played as underdogs in five of their past 10 games and won two of those contests.
• When it comes to hitting the over, the Cubs and their opponents are 6-4-0 in their last 10 games with a total.
• The Cubs have a record of 4-6-0 ATS over their last 10 games.

Cubs Recent Stats

Cubs Player Insights

• Tucker leads the Cubs with five long balls and runs batted in, driving in 19.
• In all of MLB, Tucker is 15th in home runs and fourth in RBI.
• Carson Kelly is hitting .407 with a double, a triple, four home runs and 11 walks.
• Among all major league hitters, Kelly is 28th in home runs and 23rd in RBI.
• Pete Crow-Armstrong has six doubles, a triple, three home runs and five walks while hitting .259.
• Nico Hoerner leads the Cubs with a .313 batting average.

Cubs Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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