Cubs vs. Phillies Prediction, Odds, Picks - April 25

The Philadelphia Phillies and Bryce Harper hit the field against Pete Crow-Armstrong and the Chicago Cubs on Friday, in the first game of a three-game series at Wrigley Field. The favored Cubs have -156 moneyline odds to win against the underdog Phillies, who are listed at +131. Chicago is the run-line favorite (-1.5). The over/under is 8 runs for the contest.

Take a look at everything you need to know from a betting perspective on the Cubs-Phillies game, regarding the run line, moneyline and total, plus expert picks.

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Ian Happ hits a walk-off single, sealing the Cubs' 11-10 win over Dodgers

Ian Happ hit a walk-off single, sealing the Chicago Cubs' 11-10 win over Los Angeles Dodgers.

Cubs vs. Phillies Game Information & Odds

• When: Friday, April 25, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MLB Network, MARQ, and NBCS-PH

Cubs vs. Phillies Prediction

• Score Prediction: Cubs 7, Phillies 5
• Total Prediction: Over 8 runs
• Win Probabilities: Cubs 58%, Phillies 42%

Cubs vs. Phillies Betting Insights

• The Cubs have won nine, or 75%, of the 12 games they've played as favorites this season.
• This season Chicago has won two of its three games when favored by at least -156 on the moneyline.
• The Cubs have a 60.9% chance to win this game based on the implied probability of the moneyline.
• The Phillies have won in three of the six contests they have been named as odds-on underdogs this year.
• Philadelphia has yet to play a game this season with longer moneyline odds than +131.
• The Phillies have an implied victory probability of 43.3% according to the moneyline set for this matchup.

Cubs Recent Betting Performance

• The Cubs went 3-1 over the four games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups, the Cubs and their opponents combined to hit the over on the total six times (all 10 games had set totals).
• The Cubs have a 5-5-0 record against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker leads the Cubs with seven home runs and 25 runs batted in, while putting up a team-high batting average of .314.
• Tucker's home runs place him eighth in MLB, and he is fourth in RBI.
• Crow-Armstrong has nine doubles, a triple, five home runs and six walks while batting .294.
• Crow-Armstrong ranks 32nd in homers and 21st in RBI among all MLB hitters this season.
• Crow-Armstrong heads into this game looking for his third game in a row with a hit. In his last five games he is hitting .429 with three doubles, two home runs, a walk and seven RBI.
• Carson Kelly is hitting .342 with a double, a triple, six home runs and 14 walks.
• Ian Happ is batting .268 with five doubles, two home runs and 15 walks.
• Happ has recorded at least one hit in three straight games. In his last five games he is batting .409 with a double, a home run, three walks and five RBI.

Cubs Team Props

Phillies Recent Betting Performance

• Over the past 10 games, the Phillies have been underdogs just once and lost that contest.
• When it comes to hitting the over, the Phillies and their opponents are 8-2-0 in their last 10 games with a total.
• The Phillies are 4-6-0 ATS over their last 10 games.

Phillies Recent Stats

Phillies Player Insights

• Kyle Schwarber paces the Phillies in home runs (seven) and runs batted in (16).
• Schwarber is eighth in homers and 25th in RBI among all hitters in the majors.
• Harper is batting .250 with four doubles, five home runs and 21 walks.
• Harper ranks 32nd overall in home runs and 44th in RBI this season.
• Bryson Stott paces the Phillies' lineup with a .298 batting average.
• Nicholas Alexander Castellanos is hitting .275 with six doubles, three home runs and nine walks.

Phillies Team Props

Ian Happ hits a walk-off single, sealing the Cubs' 11-10 win over Dodgers

Ian Happ hit a walk-off single, sealing the Chicago Cubs' 11-10 win over Los Angeles Dodgers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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