Cardinals vs. Nationals Prediction, Odds, Picks - May 9

Lars Nootbaar and the St. Louis Cardinals will play James Wood and the Washington Nationals on Friday at Nationals Park, at 6:45 p.m. ET. The Cardinals are the favorite in this one, at -110, while the underdog Nationals have -109 odds to upset. St. Louis is the run-line favorite (-1.5). The matchup's total is set at 8.5 runs.

Check out everything you need to know from a betting perspective on the Cardinals-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Cardinals vs. Nationals Game Information & Odds

• When: Friday, May 9, 2025 at 6:45 p.m. ET
• Where: Nationals Park in Washington D.C.
• How to watch on TV: Apple TV+

Cardinals vs. Nationals Prediction

• Score Prediction: Cardinals 5, Nationals 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Cardinals 51%, Nationals 49%

Cardinals vs. Nationals Betting Insights

• This season, the Cardinals have been favored 12 times and won six, or 50%, of those games.
• St. Louis has a record of 6-6 in games when bookmakers favor them by at least -110 on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Cardinals have a 52.4% chance to win.
• The Nationals have been underdogs in 31 games this season and have come away with the win 15 times (48.4%) in those contests.
• Washington has a win-loss record of 14-16 when favored by -109 or worse by bookmakers this year.
• The Nationals have an implied victory probability of 52.2% according to the moneyline set by sportsbooks for this matchup.

Cardinals Recent Betting Performance

• The Cardinals were the moneyline favorite for three of their last 10 games, and they went 2-1 in those matchups.
• Over their last 10 matchups -- all had a set run total -- the Cardinals and their opponents combined to hit the over on the total six times.
• The Cardinals are 7-3-0 against the spread over their past 10 games.

Cardinals Recent Stats

Cardinals Player Insights

• Nootbaar leads the Cardinals with five home runs and 19 runs batted in.
• In all of the majors, Nootbaar is 66th in home runs and 61st in RBI.
• Brendan Donovan's 19 runs batted in and .331 batting average both pace his team.
• Donovan ranks 141st in homers and 61st in RBI on the year.
• Donovan carries an eight-game streak with at least one hit into this contest. In his last 10 games he is batting .250 with a double, five walks and three RBIs.
• Nolan Arenado is batting .256 with nine doubles, three home runs and 16 walks.
• Arenado will look to build on his four-game hitting in this game. During his last five outings he is batting .316 with two walks and an RBI.
• Victor Scott II is batting .289 with six doubles, a triple, two home runs and 13 walks.
• Scott takes an eight-game streak with at least one hit into this one. During his last 10 outings he is hitting .323 with a double, a home run, five walks and five RBIs.

Cardinals Team Props

Nationals Recent Betting Performance

• The Nationals have played as underdogs in 10 of their past 10 games and won five of those contests.
• In their last 10 games with a total, the Nationals and their opponents have failed to hit the over three times.
• The Nationals have six wins against the spread in their last 10 chances.

Nationals Recent Stats

Nationals Player Insights

• Wood has swatted a team-high 10 long balls.
• Wood's home run total puts him sixth in the big leagues, and he is 28th in RBI.
• Wood carries a seven-game hitting streak into this matchup. During his last 10 games he is hitting .341 with four doubles, two home runs, seven walks and four RBIs.
• Nathaniel Lowe has collected 28 runs batted in to lead his team.
• Lowe is 48th overall in homers and 11th in RBI this year.
• C.J. Abrams is batting .286 with five doubles, two triples, four home runs and eight walks.
• Luis Garcia is batting .235 with five doubles, three home runs and 10 walks.

Nationals Team Props

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