Blue Jays vs. Rays Prediction, Odds, Picks - September 27

Joe Boyle will look to control Vladimir Guerrero Jr. and the Toronto Blue Jays when they play his Tampa Bay Rays on Saturday at 3:07 p.m. ET. The Blue Jays are the favorite in this one, at -169, while the underdog Rays have +142 odds to win. Toronto (-1.5) is favored on the run line. The total is 8.5 runs for this matchup (with -107 odds to go over and -113 odds on the under).

Here is everything you need from a betting perspective on the Blue Jays-Rays game, regarding the run line, moneyline and total, plus expert picks.

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Rays vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Tampa Bay Rays and Baltimore Orioles.

Blue Jays vs. Rays Game Information & Odds

• When: Saturday, September 27, 2025 at 3:07 p.m. ET
• Where: Rogers Centre in Toronto, Ontario
• How to watch on TV: SNET and FDSSUN

Blue Jays vs. Rays Prediction

• Score Prediction: Blue Jays 4, Rays 3
• Total Prediction: Under 8.5 runs
• Win Probabilities: Blue Jays 55%, Rays 45%

Blue Jays vs. Rays Betting Insights

• The Blue Jays have won 49, or 58.3%, of the 84 games they've played as favorites this season.
• Toronto has a record of 17-5 in games when oddsmakers favor them by at least -169 on the moneyline.
• The oddsmakers' moneyline implies a 62.8% chance of a victory for the Blue Jays.
• The Rays have been underdogs in 79 games this season and have come away with the win 33 times (41.8%) in those contests.
• This season, Tampa Bay has been victorious four times in 12 chances when named as an underdog of at least +142 or longer on the moneyline.
• The moneyline set for this matchup implies the Rays have a 41.3% chance of walking away with the win.

Blue Jays Recent Betting Performance

• The Blue Jays were favored on the moneyline for eight of their last 10 games, and they finished 3-5 in those matchups.
• Over their last 10 outings (all 10 of them had set totals), the Blue Jays and their opponents combined to hit the over four times.
• The Blue Jays have put together a 3-7-0 record against the spread over their past 10 games.

Blue Jays Recent Stats

Blue Jays Player Insights

• Guerrero has 34 doubles, 23 home runs and 81 walks while batting .295.
• Guerrero ranks 60th in home runs and 45th in RBI among all hitters in the majors.
• Guerrero carries a two-game hitting streak into this matchup. During his last five outings he is hitting .211 with a double, a walk and two RBIs.
• George Springer has hit 31 home runs to lead his team.
• Of all MLB hitters, Springer is 19th in home runs and 49th in RBI.
• Springer heads into this game looking for his third game in a row with a hit. In his last five games he is batting .300 with two doubles, a home run, three walks and three RBIs.
• Ernie Clement is hitting .275 with 34 doubles, two triples, nine home runs and 26 walks.
• Alejandro Kirk is batting .278 with 17 doubles, 12 home runs and 48 walks.

Blue Jays Team Props

Rays Recent Betting Performance

• The Rays have played as underdogs in six of their past 10 games and won four of those contests.
• In their last 10 games with a total, the Rays and their opponents have combined to hit the over five times.
• The Rays have a record of 5-5-0 ATS over their last 10 games.

Rays Recent Stats

Rays Player Insights

• Junior Caminero has posted a team-leading 45 home runs and has driven in 110 runs.
• Among all batters in MLB, Caminero ranks sixth in home runs and eighth in RBI.
• Caminero takes a hitting streak of three games into this game. During his last five outings he is batting .412 with a home run, two walks and two RBIs.
• Yandy Diaz's .299 batting average is a team-high mark.
• Diaz is 46th in home runs and 45th in RBI among all major league hitters this season.
• Brandon Lowe has 19 doubles, 31 home runs and 37 walks while hitting .258.
• Chandler Simpson has 14 doubles, three triples and 20 walks while hitting .296.

Rays Team Props

Rays vs. Orioles Highlights | MLB on FOX

Check out the best moments between the Tampa Bay Rays and Baltimore Orioles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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