Blue Jays vs. Orioles Prediction, Odds, Picks - March 29

Dean Kremer will try to shut down Anthony Santander and company when the Baltimore Orioles play the Toronto Blue Jays on Saturday at 3:07 p.m. ET, at Rogers Centre. The Orioles are +106 moneyline underdogs for this matchup with the favored Blue Jays (-126). Toronto is a 1.5-run favorite (at +159 odds). The total is 8.5 runs for this contest.

Here's everything you need from a betting perspective on the Blue Jays-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Orioles vs. Blue Jays Highlights | MLB on FOX

Check out the best highlights between the between the Baltimore Orioles and the Toronto Blue Jays.

Blue Jays vs. Orioles Game Information & Odds

• When: Saturday, March 29, 2025 at 3:07 p.m. ET
• Where: Rogers Centre in Toronto, Ontario
• How to Watch on TV: SNET and MASN2

Blue Jays vs. Orioles Prediction

• Score Prediction: Orioles 7, Blue Jays 6
• Total Prediction: Over 8.5 runs
• Win Probabilities: Blue Jays 51%, Orioles 49%

Blue Jays vs. Orioles Betting Insights

• The Blue Jays won 55% of the games last season they were favored on the moneyline (44-36).
• When playing as a moneyline favorite with odds of -126 or shorter last year, Toronto had a record of 27-22 (55.1%).
• The Blue Jays have a 55.8% chance to win this matchup based on the moneyline's implied probability.
• The Orioles won 23, or 56.1%, of the 41 games they played as underdogs last season.

Blue Jays Player Insights

• Vladimir Guerrero Jr. finished last season with a .323 average and 103 RBI.
• Santander slugged 44 long balls while driving in 102 runs.
• George Springer finished with a .220 average, 19 home runs and 56 RBI last season.
• Andres Gimenez hit .252 with an OBP of .298, and a slugging percentage of .340.

Blue Jays Team Props

Orioles Player Insights

• Adley Rutschman hit .250 last season with 21 doubles, a triple, 19 home runs and 58 walks.
• Ryan O'Hearn had 21 doubles, three triples, 15 home runs and 46 walks while batting .264.
• Cedric Mullins hit .234 a season ago with 16 doubles, three triples, 18 home runs and 41 walks.
• Colton Cowser had 24 doubles, three triples, 24 home runs and 52 walks while batting .242.

Orioles Team Props

Orioles vs. Blue Jays Highlights | MLB on FOX

Check out the best highlights between the between the Baltimore Orioles and the Toronto Blue Jays.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Toronto Blue Jays

Baltimore Orioles