Washington vs. Illinois Prediction, Odds, Picks - October 25, 2025

The No. 23 Illinois Fighting Illini (5-2) are 3.5-point underdogs in a road Big Ten matchup against the Washington Huskies (5-2) on Saturday, October 25, 2025 at Alaska Airlines Field at Husky Stadium. The over/under for the outing is set at 54.5.

Facing the Michigan Wolverines in their last contest, the Huskies lost 24-7. In their most recent contest, the Fighting Illini lost against the Ohio State Buckeyes, 34-16.

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Washington vs. Illinois Game Information & Odds

• When: Saturday, October 25, 2025 at 3:30 p.m. ET
• Location: Alaska Airlines Field at Husky Stadium in Seattle, Washington
• TV: BTN
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Washington vs. Illinois Prediction

• Pick ATS: Illinois (+3.5)
  
• Pick OU: Over (54.5)
  
• Prediction: Illinois 30, Washington 26

Predictions are made by the Data Skrive betting model.

Learn more about the Washington Huskies vs. the Illinois Fighting Illini game on FOX Sports!

Washington vs. Illinois Betting Insights

• Per the spread and over/under, the implied score for the game is Huskies 29, Fighting Illini 26.
• The Huskies have a 62.0% chance to win this game based on the moneyline's implied probability. The Fighting Illini hold a 42.0% implied probability.
• Washington has a record of 2-4-0 against the spread this season.
• Illinois has compiled a 5-2-0 ATS record so far this year.

Washington vs. Illinois: 2025 Stats Comparison

Washington 2025 Key Players

Illinois 2025 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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