UTSA vs. Colorado State Prediction, Odds, Picks - September 20, 2025

Updated Sep. 20, 2025 9:04 p.m. ET

Data Skrive

The Colorado State Rams (1-1) will look to prove oddsmakers wrong when they take on the UTSA Roadrunners (1-2) on Saturday, September 20, 2025 as 4.5-point underdogs. A total of 58.5 points has been set for this matchup.

Last time out, the Roadrunners defeated the Incarnate Word Cardinals, with 48-20 being the final score. The Rams' most recent contest was versus the Northern Colorado Bears, and they won by a score of 21-17.

Keep up with college football all season on FOX Sports.

UTSA vs. Colorado State Game Information & Odds

When: Saturday, September 20, 2025 at 9:30 p.m. ET
Location: Sonny Lubick Field at Canvas Stadium in Fort Collins, Colorado
TV: Fox Sports 1
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

UTSA vs Colorado State Betting Information updated as of September 20, 2025, 8:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
UTSA	-4.5 (-111)	-202	+167	58.5	-109	-111

UTSA vs. Colorado State Prediction

Pick ATS: UTSA (-4.5)
Pick OU: Over (58.5)
Prediction: UTSA 36, Colorado State 30

Predictions are made by the Data Skrive betting model.

Learn more about the UTSA Roadrunners vs. the Colorado State Rams game on FOX Sports!

UTSA vs. Colorado State Betting Insights

Per the spread and over/under, the implied score for the matchup is Roadrunners 32, Rams 27.
The Roadrunners have a 66.9% chance to collect the win in this contest per the moneyline's implied probability. The Rams have a 37.5% implied probability.
UTSA has a record of 2-1-0 against the spread this season.
Colorado State has won one game against the spread this year.

UTSA vs. Colorado State: 2025 Stats Comparison

	UTSA	Colorado State
Off. Points per Game (Rank)	36 (53)	21 (128)
Def. Points per Game (Rank)	35 (113)	27.5 (46)
Turnovers Allowed (Rank)	0 (1)	5 (89)
Turnovers Forced (Rank)	5 (36)	3 (77)

UTSA 2025 Key Players

Name	Position	Stats
Robert Henry	RB	480 YDS / 6 TD / 160 YPG / 10.2 YPC 9 REC / 20 REC YDS / 1 REC TD / 6.7 REC YPG
Owen McCown	QB	578 YDS (64.5%) / 6 TD / 0 INT 57 RUSH YDS / 0 RUSH TD / 19 RUSH YPG
Devin McCuin	WR	18 REC / 167 YDS / 2 TD / 55.7 YPG
AJ Wilson	WR	6 REC / 151 YDS / 2 TD / 50.3 YPG
Shadrach Banks	LB	20 TKL / 2 TFL / 2 INT / 2 PD
Kenny Ozowalu	DL	5 TKL / 4 TFL / 2 SACK
Jimmy Wyrick	DB	13 TKL / 0 TFL
Davin Martin	DB	9 TKL / 0 TFL / 1 INT / 1 PD

Colorado State 2025 Key Players

Name	Position	Stats
Jalen Dupree	RB	150 YDS / 1 TD / 75 YPG / 5.4 YPC
Brayden Fowler-Nicolosi	QB	312 YDS (52.6%) / 1 TD / 2 INT 16 RUSH YDS / 1 RUSH TD / 8 RUSH YPG
Lloyd Avant	RB	80 YDS / 2 TD / 40 YPG / 5.3 YPC
Jaxxon Warren	TE	7 REC / 95 YDS / 1 TD / 47.5 YPG
Owen Long	LB	21 TKL / 0 TFL
Lemondre Joe	DB	11 TKL / 1 TFL / 1.5 SACK
Robert Edmonson	LB	9 TKL / 1 TFL / 1 SACK
Jahari Rogers	DB	6 TKL / 0 TFL / 1 INT / 1 PD