Toledo vs. Northern Illinois Prediction, Odds, Picks - November 5, 2025

Updated Nov. 5, 2025 3:12 p.m. ET

Data Skrive

The Toledo Rockets (4-4) are double-digit, 14.5-point favorites at home at the Glass Bowl against the Northern Illinois Huskies (2-6) on Wednesday, November 5, 2025. Both squads have stout pass defenses, with the Rockets fourth against the pass in the nation, and the Huskies 15th defending the passing game. A total of 42.5 points has been set for this game.

Last time out, the Rockets fell to the Washington State Cougars, with 28-7 being the final score. Last time out, the Huskies defeated the Ball State Cardinals, with 21-7 being the final score.

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Toledo vs. Northern Illinois Game Information & Odds

When: Wednesday, November 5, 2025 at 7 p.m. ET
Location: Glass Bowl in Toledo, Ohio
TV: ESPN2
Live Box Score on FOX Sports

Toledo vs Northern Illinois Betting Information updated as of November 5, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Toledo	-14.5 (-110)	-662	+481	42.5	-107	-118

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Toledo vs. Northern Illinois Prediction

Pick ATS: Northern Illinois (+14.5)
Pick OU: Under (42.5)
Prediction: Toledo 27, Northern Illinois 13

Predictions are made by the Data Skrive betting model.

Learn more about the Toledo Rockets vs. the Northern Illinois Huskies game on FOX Sports!

Toledo vs. Northern Illinois Betting Insights

Based on the spread and over/under, the implied score for the matchup is Rockets 28, Huskies 14.
The Rockets have an 86.9% chance to collect the win in this contest based on the moneyline's implied probability. The Huskies hold a 17.2% implied probability.
Toledo has won five games against the spread this season, while failing to cover three times.
Northern Illinois has won just two games against the spread this season.

Toledo vs. Northern Illinois: Head-to-Head

Over their last four meetings, Toledo has tallied three wins versus Northern Illinois.
The two teams have gone over the point total on two occasions while sharing a split 2-2 record in their games against the spread.
In their last four head-to-head matchups, Toledo has scored 120 points against Northern Illinois, while giving up only 93 points.

Toledo vs. Northern Illinois: 2025 Stats Comparison

	Toledo	Northern Illinois
Off. Points per Game (Rank)	31.8 (60)	13.4 (134)
Def. Points per Game (Rank)	16 (9)	22.1 (37)
Turnovers Allowed (Rank)	8 (25)	10 (55)
Turnovers Forced (Rank)	13 (34)	9 (86)

Toledo 2025 Key Players

Name	Position	Stats
Tucker Gleason	QB	1,721 YDS (64.5%) / 13 TD / 5 INT 71 RUSH YDS / 3 RUSH TD / 10.1 RUSH YPG
DeaMonte Trayanum	RB	601 YDS / 7 TD / 100.2 YPG / 5.8 YPC 7 REC / 61 REC YDS / 1 REC TD / 12.2 REC YPG
Junior Vandeross III	WR	52 REC / 608 YDS / 8 TD / 76 YPG
Kenji Christian	RB	379 YDS / 2 TD / 47.4 YPG / 5.2 YPC 12 REC / 144 REC YDS / 0 REC TD / 24 REC YPG
Emmanuel McNeil-Warren	DB	49 TKL / 2 TFL / 0.5 SACK / 1 INT
Braden Awls	DB	35 TKL / 3 TFL / 0.5 SACK / 4 INT
K'Von Sherman	LB	49 TKL / 7 TFL / 1 SACK
Malachi Davis	DL	25 TKL / 8 TFL / 4.5 SACK

Northern Illinois 2025 Key Players

Name	Position	Stats
Telly Johnson Jr.	RB	559 YDS / 3 TD / 69.9 YPG / 6 YPC
DeAree Rogers	WR	38 REC / 439 YDS / 3 TD / 54.9 YPG
Chavon Wright	RB	491 YDS / 2 TD / 61.4 YPG / 4 YPC
Josh Holst	QB	602 YDS (62.4%) / 4 TD / 3 INT 141 RUSH YDS / 1 RUSH TD / 23.5 RUSH YPG
Quinton Urwiler	LB	97 TKL / 5 TFL / 1.5 SACK
Filip Maciorowski	LB	53 TKL / 1 TFL / 2.5 SACK
Jasper Beeler	DB	50 TKL / 0 TFL / 0.5 SACK / 2 INT
Muhammad Jammeh	DB	47 TKL / 1 TFL / 2 INT / 2 PD