Pittsburgh vs. West Virginia Prediction, Odds, Picks - September 13, 2025

The Pittsburgh Panthers (2-0) and the West Virginia Mountaineers (1-1) take the field for the Backyard Brawl on Saturday, September 13, 2025 at Mountaineer Field at Milan Puskar Stadium. The Panthers are 7-point favorites. The point total is set at 55.5 for the contest.

The Panthers beat the Central Michigan Chippewas, 45-17, in their last contest. The Mountaineers' most recent contest was against the Ohio Bobcats, and they lost by a score of 17-10.

Keep up with college football all season on FOX Sports.

Pittsburgh vs. West Virginia Game Information & Odds

• When: Saturday, September 13, 2025 at 3:30 p.m. ET
• Location: Mountaineer Field at Milan Puskar Stadium in Morgantown, West Virginia
• TV: ESPN
• Live Box Score on FOX Sports

Pittsburgh vs. West Virginia Prediction

• Pick ATS: West Virginia (+7)
  
• Pick OU: Under (55.5)
  
• Prediction: Pittsburgh 24, West Virginia 21

Predictions are made by the Data Skrive betting model.

Learn more about the Pittsburgh Panthers vs. the West Virginia Mountaineers game on FOX Sports!

Pittsburgh vs. West Virginia Betting Insights

• Based on the spread and over/under, the implied score for the game is Panthers 31, Mountaineers 24.
• The Panthers have a 73.6% chance to claim victory in this game based on the moneyline's implied probability. The Mountaineers have a 30.8% implied probability.
• Pittsburgh has a record of 2-0-0 against the spread this season.
• West Virginia has a record of 1-1-0 against the spread this season.

Pittsburgh vs. West Virginia: Head-to-Head

• Pittsburgh holds a 2-1 record against West Virginia in their last three matchups.
• In those matchups against Pittsburgh, the Mountaineers have covered two times while outscoring the total on two occasions.
• West Virginia has scored 82 points in its last three contests against Pittsburgh, matching the Panthers' offensive output (82 points) in those games.

Pittsburgh vs. West Virginia: 2025 Stats Comparison

Pittsburgh 2025 Key Players

West Virginia 2025 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.

FOLLOW Follow your favorites to personalize your FOX Sports experience

West Virginia Mountaineers

Pittsburgh Panthers

College Football