Ole Miss vs. Arkansas Prediction, Odds, Picks - September 13, 2025

Updated Sep. 13, 2025 3:04 p.m. ET

Data Skrive

The No. 17 Ole Miss Rebels (2-0) host the Arkansas Razorbacks (2-0) on Saturday, September 13, 2025 in a matchup between SEC foes at Vaught-Hemingway Stadium. Arkansas is a 4.5-point underdog. The point total is 59.5.

The Rebels beat the Kentucky Wildcats, 30-23, in their last game. In their most recent contest, the Razorbacks won against the Arkansas State Red Wolves, 56-14.

Keep up with college football all season on FOX Sports.

Ole Miss vs. Arkansas Game Information & Odds

When: Saturday, September 13, 2025 at 7 p.m. ET
Location: Vaught-Hemingway Stadium in Oxford, Mississippi
TV: ESPN
Live Box Score on FOX Sports

Ole Miss vs Arkansas Betting Information updated as of September 13, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Ole Miss	-4.5 (-111)	-196	+162	59.5	-111	-109

Ole Miss vs. Arkansas Prediction

Pick ATS: Ole Miss (-4.5)
Pick OU: Over (59.5)
Prediction: Ole Miss 39, Arkansas 26

Predictions are made by the Data Skrive betting model.

Learn more about the Ole Miss Rebels vs. the Arkansas Razorbacks game on FOX Sports!

Ole Miss vs. Arkansas Betting Insights

Per the spread and over/under, the implied score for the matchup is Rebels 32, Razorbacks 28.
The Rebels have a 66.2% chance to collect the win in this game per the moneyline's implied probability. The Razorbacks have a 38.2% implied probability.
Ole Miss has won one game against the spread this season.
Arkansas has won one game against the spread this year.

Ole Miss vs. Arkansas: Head-to-Head

Over their last four meetings, Ole Miss has totaled three wins against Arkansas.
In those games versus Ole Miss, the Razorbacks have covered three times while eclipsing the point total on three occasions.
In their last four head-to-head matchups, Ole Miss has compiled 169 points against Arkansas, while giving up only 144 points.

Ole Miss vs. Arkansas: 2025 Stats Comparison

	Ole Miss	Arkansas
Off. Points per Game (Rank)	46.5 (25)	54 (9)
Def. Points per Game (Rank)	15 (47)	10.5 (24)
Turnovers Allowed (Rank)	4 (108)	2 (54)
Turnovers Forced (Rank)	1 (96)	4 (19)

Ole Miss 2025 Key Players

Name	Position	Stats
Kewan Lacy	RB	246 YDS / 4 TD / 123 YPG / 5.6 YPC
Austin Simmons	QB	576 YDS (60%) / 3 TD / 4 INT 61 RUSH YDS / 1 RUSH TD / 30.5 RUSH YPG
Harrison Wallace III	WR	9 REC / 247 YDS / 1 TD / 123.5 YPG
Logan Diggs	RB	97 YDS / 1 TD / 48.5 YPG / 10.8 YPC
Zxavian Harris	DL	11 TKL / 2 TFL / 2 SACK / 1 INT
T.J. Dudley	LB	14 TKL / 0 TFL
William Echoles	DL	6 TKL / 1 TFL / 1 SACK
Princewill Umanmielen	DL	4 TKL / 2 TFL / 1 SACK

Arkansas 2025 Key Players

Name	Position	Stats
Taylen Green	QB	561 YDS (71.9%) / 10 TD / 2 INT 192 RUSH YDS / 1 RUSH TD / 96 RUSH YPG
Mike Washington	RB	195 YDS / 1 TD / 97.5 YPG / 10.8 YPC 2 REC / 26 REC YDS / 1 REC TD / 13 REC YPG
O'Mega Blake	WR	12 REC / 185 YDS / 2 TD / 92.5 YPG
CJ Brown	WR	7 REC / 85 YDS / 2 TD / 42.5 YPG
Xavian Sorey Jr.	LB	16 TKL / 1 TFL / 0.5 SACK / 1 INT
Quincy Rhodes Jr.	DL	7 TKL / 3 TFL / 3 SACK
Julian Neal	DB	14 TKL / 0 TFL / 1 INT / 1 PD
Phillip Lee	DL	7 TKL / 2 TFL / 1.5 SACK