Louisville vs. Kentucky Prediction, Odds, Picks - November 25

Updated Nov. 25, 2023 9:04 a.m. ET

FOX Sports

The No. 9 Louisville Cardinals (10-1) are 8-point favorites at home at L&N Federal Credit Union Stadium against the Kentucky Wildcats (6-5) on Saturday, November 25, 2023. Both teams feature solid rush defenses, with the Cardinals 13th against the run in the nation, and the Wildcats 22nd defending the rushing attack. The contest has an over/under of 49.5 points.

The Cardinals' most recent game was against the Miami Hurricanes, and they won by a score of 38-31. Facing the South Carolina Gamecocks in their last contest, the Wildcats lost 17-14.

Louisville vs. Kentucky Game Information & Odds

When: Saturday, November 25, 2023 at 12:00 PM ET
Location: L&N Federal Credit Union Stadium in Louisville, Kentucky
TV: ABC
Live boxscore on FOX Sports

Louisville vs Kentucky Betting Information updated as of November 25, 2023, 8:45 AM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Louisville	-8 (-112)	-311	+248	49.5	-110	-110

Louisville vs. Kentucky Prediction

Pick ATS: Louisville (-8)
Pick OU: Over (49.5)
Prediction: Louisville 34, Kentucky 18

Learn more about the Louisville Cardinals vs. the Kentucky Wildcats game on FOX Sports!

Louisville vs. Kentucky Betting Insights

Per the spread and over/under, the implied score for the tilt is Cardinals 29, Wildcats 21.
The Cardinals have a 75.7% chance to claim victory in this game per the moneyline's implied probability. The Wildcats hold a 28.7% implied probability.
Louisville has put together a 6-4-1 record against the spread this season.
Kentucky is 5-6-0 ATS this season.

Louisville vs. Kentucky: Head-to-Head

Kentucky has a 2-0 record against Louisville in their last two matchups.
In those matchups versus Louisville, the Wildcats have covered two times while outscoring the point total on one occasion.
In their last two head-to-head matchups, Kentucky has tallied 78 points versus Louisville, while surrendering only 34 points.

Louisville vs. Kentucky: 2023 Stats Comparison

	Louisville	Kentucky
Off. Points per Game (Rank)	33.2 (32)	27.7 (69)
Def. Points per Game (Rank)	18.4 (17)	24.3 (50)
Turnovers Allowed (Rank)	13 (37)	15 (61)
Turnovers Forced (Rank)	18 (30)	14 (83)

Louisville 2023 Key Players

Name	Position	Stats
Jawhar Jordan	RB	1,009 YDS / 11 TD / 91.7 YPG / 6.7 YPC 15 REC / 200 REC YDS / 1 REC TD / 18.2 REC YPG
Jack Plummer	QB	2,710 YDS (65.4%) / 19 TD / 10 INT 55 RUSH YDS / 1 RUSH TD / 5.0 RUSH YPG
Isaac Guerendo	RB	585 YDS / 8 TD / 53.2 YPG / 6.4 YPC 14 REC / 165 REC YDS / 0 REC TD / 15.0 REC YPG
Jamari Thrash	WR	50 REC / 741 YDS / 6 TD / 67.4 YPG
Ashton Gillotte	DL	29 TKL / 8.0 TFL / 9.0 SACK
Devin Neal	DB	42 TKL / 0.0 TFL / 4 INT / 4 PD
TJ Quinn	LB	59 TKL / 0.0 TFL / 0.5 SACK / 1 INT
Cam'Ron Kelly	DB	40 TKL / 0.0 TFL / 2 INT / 2 PD

Kentucky 2023 Key Players

Name	Position	Stats
Re'Mahn Davis	RB	990 YDS / 12 TD / 90.0 YPG / 5.8 YPC 25 REC / 266 REC YDS / 5 REC TD / 24.2 REC YPG
Devin Leary	QB	2,234 YDS (56.0%) / 20 TD / 9 INT -29 RUSH YDS / 1 RUSH TD / -2.6 RUSH YPG
Dane Key	WR	36 REC / 528 YDS / 4 TD / 48.0 YPG
Tayvion Robinson	WR	36 REC / 501 YDS / 4 TD / 45.5 YPG
Maxwell Hairston	DB	51 TKL / 1.0 TFL / 5 INT / 5 PD
D'Eryk Jackson	LB	65 TKL / 4.0 TFL / 1.0 SACK / 2 INT
Trevin Wallace	LB	49 TKL / 6.0 TFL / 4.5 SACK / 1 INT
Deone Walker	DL	42 TKL / 10.0 TFL / 5.5 SACK