College Football Top 25 Week 1 2025 Predictions, Betting Odds & TV Schedule

Ranked squads will be on the Week 1 college football schedule in 22 games, including the No. 1 Texas Longhorns playing the No. 3 Ohio State Buckeyes.

Check out our odds breakdown for college football's Week 1.

Check out the full college football schedule on FOX Sports! Or visit FOX Sports' college football hub for everything you need to make the most of this season’s action.

Week 1 Betting Lines & Game Info

South Florida Bulls vs. No. 25 Boise State Broncos

Odds & Prediction

• Spread: Broncos (-5.5)
• Moneyline: Broncos -205, Bulls +170
• Total: 62.5 points
• Prediction: Boise State 37, South Florida 24

How to Watch

• Game Date: Thursday, Aug. 28
• Game Time: 5:30 p.m. ET
• TV Channel: ESPN
• Location: Tampa, Florida
• Box Score

No. 12 Illinois Fighting Illini vs. Western Illinois Leathernecks

Odds & Prediction

• Spread: Fighting Illini (-48.5)
• Moneyline: Fighting Illini , Leathernecks
• Total: 63.5 points
• Prediction:

How to Watch

• Game Date: Friday, Aug. 29
• Game Time: 7:30 p.m. ET
• TV Channel: Peacock
• Location: Champaign, Illinois
• Box Score

No. 3 Ohio State Buckeyes vs. No. 1 Texas Longhorns

Odds & Prediction

• Spread: Buckeyes (-1.5)
• Moneyline: Buckeyes -118, Longhorns -102
• Total: 46.5 points
• Prediction: Ohio State 31, Texas 18

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 12 p.m. ET
• TV Channel: FOX
• Location: Columbus, Ohio
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

No. 24 Tennessee Volunteers vs. Syracuse Orange

Odds & Prediction

• Spread: Volunteers (-13.5)
• Moneyline: Volunteers -521, Orange +390
• Total: 51.5 points
• Prediction: Tennessee 34, Syracuse 23

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 12 p.m. ET
• TV Channel: ABC
• Location: Atlanta, Georgia
• Box Score

No. 20 Indiana Hoosiers vs. Old Dominion Monarchs

Odds & Prediction

• Spread: Hoosiers (-22.5)
• Moneyline: Hoosiers -2381, Monarchs +1200
• Total: 53.5 points
• Prediction: Indiana 41, Old Dominion 15

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 2:30 p.m. ET
• TV Channel: FS1
• Location: Bloomington, Indiana
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

No. 5 Georgia Bulldogs vs. Marshall Thundering Herd

Odds & Prediction

• Spread: Bulldogs (-38.5)
• Moneyline: Bulldogs , Thundering Herd
• Total: 52.5 points
• Prediction: Georgia 34, Marshall 19

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 3:30 p.m. ET
• TV Channel: ESPN
• Location: Athens, Georgia
• Box Score

No. 22 Iowa State Cyclones vs. South Dakota Coyotes

Odds & Prediction

• Spread: Cyclones (-16.5)
• Moneyline: Cyclones -800, Coyotes +550
• Total: 47.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 3:30 p.m. ET
• TV Channel: FOX
• Location: Ames, Iowa
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

No. 2 Penn State Nittany Lions vs. Nevada Wolf Pack

Odds & Prediction

• Spread: Nittany Lions (-42.5)
• Moneyline: Nittany Lions , Wolf Pack
• Total: 54.5 points
• Prediction: Penn State 46, Nevada 5

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 3:30 p.m. ET
• TV Channel: CBS
• Location: University Park, Pennsylvania
• Box Score

Florida State Seminoles vs. No. 8 Alabama Crimson Tide

Odds & Prediction

• Spread: Crimson Tide (-14)
• Moneyline: Crimson Tide -599, Seminoles +440
• Total: 47.5 points
• Prediction: Alabama 36, Florida State 11

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 3:50 p.m. ET
• TV Channel: ABC
• Location: Tallahassee, Florida
• Box Score

No. 7 Oregon Ducks vs. Montana State Bobcats

Odds & Prediction

• Spread: Ducks (-28.5)
• Moneyline: Ducks -7692, Bobcats +2200
• Total: 57.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 4 p.m. ET
• TV Channel: BTN
• Location: Eugene, Oregon
• Box Score

No. 18 Oklahoma Sooners vs. Illinois State Redbirds

Odds & Prediction

• Spread: Sooners (-39.5)
• Moneyline: Sooners , Redbirds
• Total: 60.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 6 p.m. ET
• TV Channel: SEC Network+
• Location: Norman, Oklahoma
• Box Score

No. 15 Florida Gators vs. LIU Sharks

Odds & Prediction

• Spread: Gators (-45.5)
• Moneyline: Gators , Sharks
• Total: 57.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7 p.m. ET
• TV Channel: SEC Network+
• Location: Gainesville, Florida
• Box Score

No. 19 Texas A&M Aggies vs. UTSA Roadrunners

Odds & Prediction

• Spread: Aggies (-23.5)
• Moneyline: Aggies -2083, Roadrunners +1100
• Total: 58.5 points
• Prediction: Texas A&M 40, UTSA 18

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7 p.m. ET
• TV Channel: ESPN
• Location: College Station, Texas
• Box Score

No. 17 Kansas State Wildcats vs. North Dakota Fighting Hawks

Odds & Prediction

• Spread: Wildcats (-27.5)
• Moneyline: Wildcats -7692, Fighting Hawks +2200
• Total: 55.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7 p.m. ET
• TV Channel: ESPN+
• Location: Manhattan, Kansas
• Box Score

No. 14 Michigan Wolverines vs. New Mexico Lobos

Odds & Prediction

• Spread: Wolverines (-34.5)
• Moneyline: Wolverines -20000, Lobos +3500
• Total: 48.5 points
• Prediction: Michigan 44, New Mexico 13

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7:30 p.m. ET
• TV Channel: NBC
• Location: Ann Arbor, Michigan
• Box Score

No. 4 Clemson Tigers vs. No. 9 LSU Tigers

Odds & Prediction

• Spread: Tigers (-4.5)
• Moneyline: Tigers -205, Tigers +170
• Total: 55.5 points
• Prediction: Clemson 28, LSU 27

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7:30 p.m. ET
• TV Channel: ABC
• Location: Clemson, South Carolina
• Box Score

No. 23 Texas Tech Red Raiders vs. Arkansas-Pine Bluff Golden Lions

Odds & Prediction

• Spread: Red Raiders (-54.5)
• Moneyline: Red Raiders , Golden Lions
• Total: 62.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7:30 p.m. ET
• TV Channel: ESPN+
• Location: Lubbock, Texas
• Box Score

No. 21 Ole Miss Rebels vs. Georgia State Panthers

Odds & Prediction

• Spread: Rebels (-33.5)
• Moneyline: Rebels , Panthers
• Total: 60.5 points
• Prediction: Ole Miss 47, Georgia State 8

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 7:45 p.m. ET
• TV Channel: SEC Network
• Location: Oxford, Mississippi
• Box Score

No. 16 SMU Mustangs vs. East Texas A&M Lions

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 9 p.m. ET
• TV Channel: ACC Network
• Location: University Park, Texas
• Box Score

No. 11 Arizona State Sun Devils vs. Northern Arizona Lumberjacks

Odds & Prediction

• Spread: Sun Devils (-28.5)
• Moneyline: Sun Devils -9091, Lumberjacks +2500
• Total: 52.5 points
• Prediction:

How to Watch

• Game Date: Saturday, Aug. 30
• Game Time: 10 p.m. ET
• TV Channel: ESPN+
• Location: Tempe, Arizona
• Box Score

No. 13 South Carolina Gamecocks vs. Virginia Tech Hokies

Odds & Prediction

• Spread: Gamecocks (-7)
• Moneyline: Gamecocks -270, Hokies +220
• Total: 52.5 points
• Prediction: South Carolina 30, Virginia Tech 19

How to Watch

• Game Date: Sunday, Aug. 31
• Game Time: 3 p.m. ET
• TV Channel: ESPN
• Location: Atlanta, Georgia
• Box Score

No. 10 Miami (FL) Hurricanes vs. No. 6 Notre Dame Fighting Irish

Odds & Prediction

• Spread: Fighting Irish (-3)
• Moneyline: Fighting Irish -148, Hurricanes +124
• Total: 50.5 points
• Prediction: Notre Dame 34, Miami (FL) 26

How to Watch

• Game Date: Sunday, Aug. 31
• Game Time: 7:30 p.m. ET
• TV Channel: ABC
• Location: Miami Gardens, Florida
• Box Score

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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