BYU vs. East Carolina Prediction, Odds, Picks - September 20, 2025

Updated Sep. 20, 2025 3:04 p.m. ET

FOX Sports

The East Carolina Pirates (2-1) will attempt to defy oddsmakers when they play the BYU Cougars (2-0) on Saturday, September 20, 2025 as 6.5-point underdogs. The game's point total is set at 49.5.

The Cougars won against the Stanford Cardinal in their last game, 27-3. The Pirates beat the Coastal Carolina Chanticleers, 38-0, in their last game.

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BYU vs. East Carolina Game Information & Odds

When: Saturday, September 20, 2025 at 7:30 p.m. ET
Location: Bagwell Field at Dowdy-Ficklen Stadium in Greenville, North Carolina
TV: ESPN2
Live Box Score on FOX Sports

BYU vs East Carolina Betting Information updated as of September 20, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
BYU	-6.5 (-110)	-235	+193	49.5	-108	-116

BYU vs. East Carolina Prediction

Pick ATS: East Carolina (+6.5)
Pick OU: Under (49.5)
Prediction: BYU 20, East Carolina 14

Predictions are made by the Data Skrive betting model.

Learn more about the BYU Cougars vs. the East Carolina Pirates game on FOX Sports!

BYU vs. East Carolina Betting Insights

Per the spread and over/under, the implied score for the game is Cougars 28, Pirates 22.
The Cougars have a 70.1% chance to claim victory in this game per the moneyline's implied probability. The Pirates hold a 34.1% implied probability.
BYU has won all two of its games against the spread this season.
East Carolina has won three games against the spread this year, failing to cover zero times.

BYU vs. East Carolina: 2025 Stats Comparison

	BYU	East Carolina
Off. Points per Game (Rank)	48 (58)	37 (37)
Def. Points per Game (Rank)	1.5 (1)	9 (12)
Turnovers Allowed (Rank)	1 (10)	1 (10)
Turnovers Forced (Rank)	4 (47)	8 (1)

BYU 2025 Key Players

Name	Position	Stats
Bear Bachmeier	QB	272 YDS (63.2%) / 3 TD / 0 INT 39 RUSH YDS / 3 RUSH TD / 19.5 RUSH YPG
LJ Martin	RB	241 YDS / 0 TD / 120.5 YPG / 9.3 YPC
Cody Hagen	WR	2 REC / 35 YDS / 0 TD / 35 YPG
Chase Roberts	WR	6 REC / 88 YDS / 1 TD / 44 YPG
Faletau Satuala	DB	6 TKL / 2 TFL / 1 INT / 1 PD
Jack Kelly	LB	4 TKL / 1 TFL / 1 SACK
Isaiah Glasker	LB	4 TKL / 1 TFL / 1 SACK
Keanu Tanuvasa	DL	3 TKL / 1 TFL / 1 SACK

East Carolina 2025 Key Players

Name	Position	Stats
Katin Houser	QB	973 YDS (71.6%) / 5 TD / 1 INT 42 RUSH YDS / 0 RUSH TD / 14 RUSH YPG
Brock Spalding	WR	13 REC / 221 YDS / 1 TD / 73.7 YPG
Yannick Smith	WR	14 REC / 136 YDS / 2 TD / 45.3 YPG
London Montgomery	RB	108 YDS / 2 TD / 36 YPG / 3.6 YPC
Jasiyah Robinson	DL	3 TKL / 1 TFL / 2 SACK
Kendrick DuJour	DL	4 TKL / 0 TFL / 1.5 SACK
Ja'Marley Riddle	DB	10 TKL / 0 TFL / 1 INT / 1 PD
Preston Carr	DL	5 TKL / 1 TFL / 1 SACK