Baylor vs. Oklahoma State Prediction, Odds, Picks - September 27, 2025

Big 12 rivals meet when the Baylor Bears (2-2) visit the Oklahoma State Cowboys (1-2) on Saturday, September 27, 2025 at Boone Pickens Stadium. Baylor is favored by 21 points. The total has been set at 58.5 points for this game.

In their last game, the Bears lost against the Arizona State Sun Devils, 27-24. The Cowboys lost to the Tulsa Golden Hurricane, 19-12, in their last contest.

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Baylor vs. Oklahoma State Game Information & Odds

• When: Saturday, September 27, 2025 at 3:30 p.m. ET
• Location: Boone Pickens Stadium in Stillwater, Oklahoma
• TV: ESPN2
• Live Box Score on FOX Sports

Baylor vs. Oklahoma State Prediction

• Pick ATS: Baylor (-21)
  
• Pick OU: Over (58.5)
  
• Prediction: Baylor 46, Oklahoma State 14

Predictions are made by the Data Skrive betting model.

Learn more about the Baylor Bears vs. the Oklahoma State Cowboys game on FOX Sports!

Baylor vs. Oklahoma State Betting Insights

• Per the spread and over/under, the implied score for the game is Bears 40, Cowboys 19.
• The Bears have a 93.9% chance to claim victory in this game based on the moneyline's implied probability. The Cowboys have a 10.5% implied probability.
• Baylor has covered once in four matchups with a spread this season.
• Oklahoma State is winless against the spread this year (0-3-0).

Baylor vs. Oklahoma State: Head-to-Head

• In their past four matchups, Oklahoma State holds a split 2-2 record against Baylor.
• The Bears and the Cowboys have matched up evenly over their last four meetings, holding a split 2-2 record against the spread. In those four head-to-head matchups, the two teams have gone over the point total on two occasions.
• Baylor has been outpaced by 6 points in its last four tilts against Oklahoma State.

Baylor vs. Oklahoma State: 2025 Stats Comparison

Baylor 2025 Key Players

Oklahoma State 2025 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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