Baylor vs. Oklahoma State Prediction, Odds, Picks - September 27, 2025

Updated Sep. 27, 2025 3:04 p.m. ET

Data Skrive

Big 12 rivals meet when the Baylor Bears (2-2) visit the Oklahoma State Cowboys (1-2) on Saturday, September 27, 2025 at Boone Pickens Stadium. Baylor is favored by 21 points. The total has been set at 58.5 points for this game.

In their last game, the Bears lost against the Arizona State Sun Devils, 27-24. The Cowboys lost to the Tulsa Golden Hurricane, 19-12, in their last contest.

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Baylor vs. Oklahoma State Game Information & Odds

When: Saturday, September 27, 2025 at 3:30 p.m. ET
Location: Boone Pickens Stadium in Stillwater, Oklahoma
TV: ESPN2
Live Box Score on FOX Sports

Baylor vs Oklahoma State Betting Information updated as of September 27, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Baylor	-21 (-110)	-1538	+852	58.5	-110	-109

Baylor vs. Oklahoma State Prediction

Pick ATS: Baylor (-21)
Pick OU: Over (58.5)
Prediction: Baylor 46, Oklahoma State 14

Predictions are made by the Data Skrive betting model.

Learn more about the Baylor Bears vs. the Oklahoma State Cowboys game on FOX Sports!

Baylor vs. Oklahoma State Betting Insights

Per the spread and over/under, the implied score for the game is Bears 40, Cowboys 19.
The Bears have a 93.9% chance to claim victory in this game based on the moneyline's implied probability. The Cowboys have a 10.5% implied probability.
Baylor has covered once in four matchups with a spread this season.
Oklahoma State is winless against the spread this year (0-3-0).

Baylor vs. Oklahoma State: Head-to-Head

In their past four matchups, Oklahoma State holds a split 2-2 record against Baylor.
The Bears and the Cowboys have matched up evenly over their last four meetings, holding a split 2-2 record against the spread. In those four head-to-head matchups, the two teams have gone over the point total on two occasions.
Baylor has been outpaced by 6 points in its last four tilts against Oklahoma State.

Baylor vs. Oklahoma State: 2025 Stats Comparison

	Baylor	Oklahoma State
Off. Points per Game (Rank)	34.5 (35)	14 (135)
Def. Points per Game (Rank)	29.3 (115)	31.7 (78)
Turnovers Allowed (Rank)	7 (117)	2 (17)
Turnovers Forced (Rank)	5 (50)	2 (116)

Baylor 2025 Key Players

Name	Position	Stats
Sawyer Robertson	QB	1,320 YDS (62.6%) / 13 TD / 3 INT
Bryson Washington	RB	415 YDS / 4 TD / 103.8 YPG / 5 YPC 9 REC / 41 REC YDS / 0 REC TD / 10.3 REC YPG
Josh Cameron	WR	21 REC / 309 YDS / 3 TD / 77.3 YPG
Michael Trigg	TE	18 REC / 222 YDS / 3 TD / 55.5 YPG
Keaton Thomas	LB	28 TKL / 0 TFL
Travion Barnes	LB	9 TKL / 1 TFL / 1 SACK
Devyn Bobby	DB	15 TKL / 0 TFL
Kendrick Simpkins	DB	5 TKL / 1 TFL / 1 SACK

Oklahoma State 2025 Key Players

Name	Position	Stats
Zane Flores	QB	417 YDS (57%) / 0 TD / 2 INT 58 RUSH YDS / 1 RUSH TD / 19.3 RUSH YPG
Rodney Fields Jr.	RB	143 YDS / 0 TD / 71.5 YPG / 5.3 YPC 6 REC / 39 REC YDS / 0 REC TD / 39 REC YPG
Hauss Hejny	QB	96 YDS (50%) / 1 TD / 0 INT 27 RUSH YDS / 1 RUSH TD / 27 RUSH YPG
Gavin Freeman	WR	9 REC / 84 YDS / 1 TD / 28 YPG
Brandon Rawls	LB	26 TKL / 1 TFL / 1 SACK
Parker Robertson	DB	20 TKL / 2 TFL
Wendell Gregory	LB	8 TKL / 5 TFL / 3 SACK
Bryan McCoy	LB	28 TKL / 0 TFL