St. John's vs. DePaul Prediction, How to Watch, Odds, Channel - Dec 16

Updated Dec. 16, 2025 8:27 p.m. ET

Data Skrive

The No. 22 St. John's Red Storm (6-3, 0-0 Big East) will host the DePaul Blue Demons (8-3, 0-0 Big East) after winning five straight home games. The contest begins at 7 p.m. ET on Tuesday, December 16, 2025.

The Red Storm head into their game against the Blue Demons as heavy favorites. The Red Storm are favored by 19.5 points. The point total for the matchup is set at 148.5.

Keep scrolling to get all you need to know before betting on the St. John's-DePaul contest.

St. John's vs. DePaul How to Watch & Odds

When: Tuesday, December 16, 2025 at 7 p.m. ET
Where: Carnesecca Arena in Queens, New York
TV: Peacock
Live Box Score: FOX Sports

Red Storm vs Blue Demons Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Red Storm	-19.5	-110	-110	148.5	-106	-114	-3704	+1350

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St. John's vs. DePaul Prediction

Pick ATS: DePaul (+19.5)
Pick OU: Over (148.5)
Prediction: St. John's 86, DePaul 68

Learn more about the St. John's Red Storm vs. the DePaul Blue Demons game on FOX Sports!

St. John's vs. DePaul Betting Insights

Betting Line Implied Predictions

Based on the spread and over/under, the implied score for the matchup is Red Storm 84, Blue Demons 64.
The Red Storm have a 97.4% chance to win this contest based on the moneyline's implied probability.
The Blue Demons hold a 6.9% implied probability to come out on top.

Key Spread Facts

St. John's has put together a 5-4-0 ATS record so far this year.
DePaul has won six games against the spread this season, while failing to cover five times.
St. John's has been favored by 19.5 points or more four times this season, and covered the spread in three of those games.

Key Total Facts

The Red Storm and their opponent have broken the 148.5-point mark seven times this season.
Blue Demons games have gone over 148.5 points on five occasions this season.
The Red Storm and Blue Demons combine to average 166.3 points per contest, which is 17.8 more than the total for this game.

Key Moneyline Facts

St. John's has won six of eight games when the moneyline favorite this season (75%).
DePaul has been underdogs in three games this season and won one (33.3%) of those contests.
St. John's has won all four games it played as a moneyline favorite with odds of -3704 or shorter.
DePaul has not entered a game this season with longer moneyline odds than +1350.

St. John's vs. DePaul: Recent Results

Red Storm vs Blue Demons Recent Games
Date	Favorite	Spread	Total	Favorite Moneyline	Underdog Moneyline	Result
2/19/2025	Red Storm	-11.5	142.5	-855	+577	82-58 STJOHN
12/17/2024	Red Storm	-11.5	151.5	-813	+556	89-61 STJOHN

St. John's vs. DePaul: 2025-26 Stats Comparison

	St. John's	DePaul
Points Scored Per Game (Rank)	88.9 (26)	77.4 (187)
Points Allowed (Rank)	73 (178)	67.8 (69)
Rebounds (Rank)	12.3 (28)	8.5 (275)
3pt Made (Rank)	7.7 (198)	7.8 (190)
Assists (Rank)	16.4 (78)	17.1 (59)
Turnovers (Rank)	13 (285)	11.3 (145)

St. John's 2025-26 Key Players

Red Storm Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Bryce Hopkins	9	14.9	5	2.7	0.9	0.3	0.9
Zuby Ejiofor	9	14.4	7.2	2.8	0.8	2.7	0.3
Oziyah Sellers	9	11.9	3.7	1.9	0.6	0.2	2.1
Ian Jackson	9	11.7	2.8	1.2	0.6	0.1	1.4
Dillon Mitchell	9	10.4	6.2	2.7	1.9	1.2	0

DePaul 2025-26 Key Players

Blue Demons Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
CJ Gunn	11	14.2	3.5	1.8	1	0.6	1.6
Layden Blocker	11	11.5	2.4	3.5	1.9	0	0.8
N.J. Benson	11	11.3	6.6	1.3	0.1	1.2	0
Kruz McClure	11	8	1.9	2.4	0.8	0.1	1.4
Kaleb Banks	11	7.7	2.7	0.9	0.4	0.3	1.1