Northwestern vs. DePaul Prediction, How to Watch, Odds, Channel - Nov 14

Updated Nov. 14, 2025 8:27 p.m. ET

Data Skrive

The Northwestern Wildcats (3-0) aim to extend a three-game winning streak when they visit the DePaul Blue Demons (2-1) at 8:30 p.m. ET on Friday, November 14, 2025 at Wintrust Arena. The matchup airs on truTV.

The Wildcats hit the court as 5.5-point favorites against the Blue Demons. The game's point total is set at 145.5.

Continue scrolling to get everything you need to know ahead of betting on the Northwestern-DePaul contest.

Northwestern vs. DePaul How to Watch & Odds

When: Friday, November 14, 2025 at 8:30 p.m. ET
Where: Wintrust Arena in Chicago, Illinois
TV: truTV
Live Box Score: FOX Sports

Wildcats vs Blue Demons Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Wildcats	-5.5	-105	-116	145.5	-112	-108	-235	+192

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Northwestern vs. DePaul Prediction

Pick ATS: Northwestern (-5.5)
Pick OU: Under (145.5)
Prediction: Northwestern 75, DePaul 63

Learn more about the Northwestern Wildcats vs. the DePaul Blue Demons game on FOX Sports!

Northwestern vs. DePaul Betting Insights

Betting Line Implied Predictions

Per the spread and over/under, the implied score for the game is Wildcats 76, Blue Demons 70.
The Wildcats have a 70.1% chance to win this game based on the moneyline's implied probability.
The Blue Demons sit with a 34.2% implied probability to come out on top.

Key Spread Facts

Northwestern won 17 games against the spread last season, while failing to cover or pushing 16 times.
DePaul compiled a 17-17-0 ATS record last year.
Northwestern had an ATS record of 4-4-1 when playing as at least a 5.5-point favorite last season.
When playing as at least a 5.5-point underdogs last season, DePaul had an ATS record of 7-11.

Key Total Facts

A total of 13 times last year, the Wildcats and their opponent combined to score more than 145.5 points.
Last year, 20 Blue Demons games featured over 145.5 points scored.
Last season, the two teams averaged a combined 144.8 points per contest, 0.7 fewer than the total for this matchup.

Key Moneyline Facts

Northwestern was the moneyline favorite 15 total times last season. It finished 13-2 in those games.
DePaul won four, or 17.4%, of the 23 games it played as underdogs last season.
Northwestern had a record of 8-1 when playing as a moneyline favorite with odds of -235 or shorter last year (88.9%).
Last season, DePaul won two of its 18 games, or 11.1%, when it was the underdog by at least +192 on the moneyline.

Northwestern vs. DePaul: Recent Results

Wildcats vs Blue Demons Recent Games
Date	Favorite	Spread	Total	Favorite Moneyline	Underdog Moneyline	Result
12/21/2024	Wildcats	-6.5	137	-277	+226	84-64 NW

Northwestern vs. DePaul: 2024-25 Stats Comparison

	Northwestern	DePaul
Points Scored Per Game (Rank)	72.4 (218)	72.4 (218)
Points Allowed (Rank)	69.2 (85)	74.5 (251)
Rebounds (Rank)	9.2 (149)	7.6 (283)
3pt Made (Rank)	6.7 (286)	9.2 (53)
Assists (Rank)	14.5 (105)	15.4 (61)
Turnovers (Rank)	9.3 (25)	11.8 (246)

Northwestern 2024-25 Top Performers

Wildcats Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Nick Martinelli	33	20.5	6.2	1.8	0.7	0.2	1
Brooks Barnhizer	17	17.1	8.8	4.2	2.3	1.1	1
Jalen Leach	23	14.3	2.1	3.4	1	0.1	1.7
Ty Berry	33	10.6	3.6	1.3	1.2	0.2	2.2
K.J. Windham	29	5.6	1.1	2	0.7	0.1	0.9

DePaul 2024-25 Top Performers

Blue Demons Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
CJ Gunn	32	12.9	4	1	1.3	0.4	1.7
Isaiah Rivera	34	10.7	4.1	1.6	0.9	0.4	2.1
Layden Blocker	33	9.5	2.9	3.1	1.1	0.2	0.9
N.J. Benson	28	9	6.2	0.9	0.4	1.4	0
Jacob Meyer	33	8.9	2.6	0.7	0.7	0.1	1.3