Washington Commanders vs. San Francisco 49ers - Odds - October 19, 2026

Commanders

0-0

OCT 20, 12:15AM

ABC

1-0

49ers

1-0

ODDS

Washington Commanders

WAS

San Francisco 49ers

WAS 32%

+190

SF 68%

-255

SPREAD

TEAM TO WIN

TOTAL

Washington Commanders

WAS

San Francisco 49ers

FOX FACTS

INSIGHT

The 49ers had recorded 109.85 passer rating in the red zone, the highest in the NFL for the 2025 regular season.

INSIGHT

The 49ers had 20 sacks, the fewest in the NFL for the 2025 regular season.

INSIGHT

The Commanders had recorded 47 redzone targets in the red zone, the fewest in the NFL for the 2025 regular season.

PLAYER NEWS

Christian McCaffrey SF #23 · RB

McCaffrey rushed 10 times for 68 yards and brought in five of eight targets for 20 yards during the 49ers' 27-7 Week 1 win over the Rams in Melbourne, Australia.

Jacory Croskey-Merritt WAS #22 · RB

Croskey-Merritt (groin) will play in Sunday's game against the Eagles, Tashan Reed reports after Commanders coach Dan Quinn's update Friday.

Deebo Samuel Sr. SF #19 · WR

Samuel brought in six of seven targets for 48 yards and a touchdown, rushed once for 12 yards and returned two kickoffs for 74 yards during the 49ers' 27-7 Week 1 win over the Rams in Melbourne, Australia.