James Thompson Jr. - NFL News, Rumors, & Updates

Cleared for Week 6 Thompson (ankle) doesn't carry an injury designation into Monday night's game against the Commanders.

Impact Thompson hasn't played since Week 2 against the Dolphins after playing 35 percent of the defensive snaps across the first two weeks of the season. He'll slide back into his depth role along the defensive line before Osa Odighizuwa and Naquan Jones.

OCTOBER 18 • ROTOWIRE

The 49ers open the practice window for WR Christian Kirk

The San Francisco 49ers opened the 21-day practice window for receiver Christian Kirk, giving the team another possible option to bolster an injury-filled position group

OCTOBER 16 • Associated Press

Approaching return to action Thompson (ankle) could return to action in Week 6 against Washington, Matt Barrows of The Athletic reports.

Impact Thompson has been sidelined since suffering a high-ankle sprain in Week 2 against Miami, but head coach Kyle Shanahan said Monday that the defensive lineman has "a chance" to play in the team's Week 6 matchup against the Commanders on Monday Night Football. Thompson has registered four total tackles (one solo) over two games this season.

OCTOBER 12 • ROTOWIRE

49ers receiver Deebo Samuel will miss time with hamstring injury

San Francisco 49ers receiver Deebo Samuel will miss at least a few weeks after injuring his hamstring in a win over the Seattle Seahawks

OCTOBER 12 • Associated Press

Won't play against Seattle Thompson (ankle) has been ruled out for Sunday's game against the Seahawks.

Impact As expected, Thompson will miss a third consecutive game due to an ankle injury. He didn't practice once during Week 5 prep, so he'll need to return to the field to have a realistic shot of being available for Week 6 against the Commanders on Monday, Oct. 19. Naquan Jones and Sebastian Valdez will both see an uptick in rotational snaps at defensive tackle behind Osa Odighizuwa and Gracen Halton.

OCTOBER 10 • ROTOWIRE

49ers DE Mykel Williams excited to get back on the field for 1st time since knee surgery

Defensive end Mykel Williams has spent nearly a year working his way back after a torn knee ligament cut short his rookie season for the San Francisco 49ers

OCTOBER 8 • Associated Press

Expects to be out again at Seattle Coach Kyle Shanahan said Monday that Thompson (ankle) is not expected back for Week 5, Cam Inman of The San Jose Mercury News reports.

Impact Thompson has already missed the 49ers' last two games with an ankle injury he picked up in Week 2 versus the Dolphins, and it seems like he's trending towards missing another contest come Sunday. In that case, Sebastian Valdez would be a candidate for increased snaps on the defensive line.

OCTOBER 6 • ROTOWIRE

The 49ers become 1st team in 21 years to allow no sacks in 1st 4 games

Any questions about the San Francisco 49ers’ offensive line after getting overwhelmed in two late-season losses to Seattle last season have been quieted with an impressive start th...

OCTOBER 5 • Associated Press

WR Mike Evans will be a game-time decision for the 49ers against the Broncos

San Francisco 49ers receiver Mike Evans will be a game-time decision Sunday against the Denver Broncos after leaving last week’s game with a rib injury

OCTOBER 2 • Associated Press

Mykel Williams has practice window opened for the injury-riddled 49ers

The injury-riddled San Francisco 49ers moved a step closer to getting a key player back for a change with the team opening the practice window for defensive end Mykel Williams

SEPTEMBER 30 • Associated Press

Won't play Week 4 Thompson (ankle) won't play in San Francisco's Week 4 matchup versus the Broncos, Jennifer Lee Chan of NBC Sports Bay Area reports.

Impact Thompson is in line to miss a second consecutive game due to the high-ankle sprain he suffered during the Week 2 win over the Dolphins. While there's currently no timetable for his return, his next chance to play will be the Week 6 matchup against Seattle.

SEPTEMBER 29 • ROTOWIRE

Sidelined versus Arizona Thompson (ankle) is listed as out for Sunday's game against Arizona.

Impact Thompson suffered a high-ankle sprain in the 35-13 victory over the Dolphins in Week 2. While nothing has been made official, an injury of this nature likely means he will miss more time moving ahead. The rookie appeared in both of the 49ers' games to begin the 2026 campaign, amassing four total tackles (one solo).

SEPTEMBER 26 • ROTOWIRE

49ers star pass rusher Nick Bosa will miss a few games after hurting his calf

San Francisco 49ers star pass rusher Nick Bosa injured his calf warming up for practice earlier this week and will miss a few games

SEPTEMBER 25 • Associated Press

The 49ers lose another defensive tackle to injury with C.J. West going on IR

The San Francisco 49ers lost another key contributor when they placed defensive tackle C

SEPTEMBER 23 • Associated Press

Likely to miss action moving forward Thompson suffered a high-ankle sprain during Sunday's 35-13 win over Miami, David Lombardi of SFStandard.com reports.

Impact Thompson sustained the injury in the second half of the victory, and he will now likely be forced to miss some time moving forward. In his absence, the 49ers will have to add another interior defensive lineman to their active roster.

SEPTEMBER 21 • ROTOWIRE

Brock Purdy and the 49ers' offense are off to an efficient start

Brock Purdy and the San Francisco 49ers offense couldn't be off to a much more efficient start to the season

SEPTEMBER 21 • Associated Press

49ers losing James Thompson may secretly be worse than Demarcus Robinson injury The 49ers lost both Demarcus Robinson and James Thompson Jr. to ankle injuries against the Dolphins, but the latter's injury might cause mor...

SEPTEMBER 21 • NINERNOISE.COM

Dealing with ankle injury Thompson (ankle) is questionable to return to Sunday's contest against Miami, Eric Branch of the San Francisco Chronicle reports.

Impact Thompson was slow to get up before ultimately going to the locker room in the second half. His status for the rest of the game is now in the air, but his absence won't have a major impact on the team's defensive approach.

SEPTEMBER 20 • ROTOWIRE

49ers DT Alfred Collins out for season after injuring knee in Melbourne, coach Shanahan says

San Francisco 49ers coach Kyle Shanahan says defensive tackle Alfred Collins is out for the season after tearing his patellar tendon

SEPTEMBER 9 • Associated Press

Nick Bosa returns to 49ers practice and is confident he will play the opener

San Francisco 49ers star pass rusher Nick Bosa was back at practice for the first time in nearly a month and is confident that he will be able to play the season opener in Australi...

SEPTEMBER 2 • Associated Press

49ers rookie DT Gracen Halton impresses in his first preseason game

The San Francisco 49ers are excited about what they've seen so far from Gracen Halton

AUGUST 17 • Associated Press

Two Undrafted 49ers Are Turning Heads Early in Training Camp Bryson Eason and James Thompson are taking advantage of injuries along the San Francisco 49ers' defensive line, earning praise from Raheem M...

AUGUST 3 • SI.COM

49ers 2026 roster ranking: No. 75-74 Will Bradley-King and James Thompson will be competing to make the San Francisco 49ers roster in 2026

JUNE 15 • SI.COM

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