Duke vs. Lehigh Prediction, Odds, Picks – Women's Basketball NCAA Tournament First Round 2025

The No. 15 Lehigh Mountain Hawks (27-6) are 28.5-point underdogs to move on to the second round of the NCAA Tournament when they face off against the No. 2 Duke Blue Devils (26-7) on Friday. Here are some insights into this 2-15 matchup that tips off at 8 p.m. ET, live on ESPNU. The matchup's point total is set at 130.5.

Duke vs. Lehigh Game Info

• Game day: Friday, March 21, 2025
• Game time: 8 p.m. ET
• TV channel: ESPNU
• Follow this game live on FOX Sports

Duke vs. Lehigh Odds

Duke vs. Lehigh Prediction

• Computer Pick ATS: Lehigh (+28.5)
  
• Computer Pick OU: Under (130.5)
  
• Computer Prediction: Duke 78, Lehigh 52

Learn more about the Duke Blue Devils vs. the Lehigh Mountain Hawks game on FOX Sports!

Duke Betting Insights

• Against the spread, the Blue Devils are 21-10-0 this season.
• Duke has two wins ATS (2-1) as a 28.5-point favorite or greater this season.
• This year, 10 of the Blue Devils' 31 games have hit the over.

Lehigh Betting Insights

Duke's Top Performers

Lehigh's Top Performers

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Duke Blue Devils

Lehigh Mountain Hawks