Arsenal FC vs. Manchester City Prediction, Odds, Picks - Sep 21

Arsenal FC vs. Manchester City Prediction, Odds, Picks - Sep 21

Updated Sep. 21, 2025 8:55 a.m. ET
Data Skrive

Both Arsenal FC (third in the Premier League) and Manchester City (12th) are coming off a victory, and they will face off on Sunday. For our prediction on this matchup, keep reading.

In the Premier League, Arsenal has put up nine goals in 4 matches (fourth in league), and Manchester City has conceded four in 4 matches (sixth). In the Premier League, Manchester City has put up eight goals in 4 games (fifth in league), and Arsenal has allowed one in 4 games (first). In terms of goal differential, Arsenal is first in the Premier League at +8. In terms of goal differential, Manchester City is fifth in the Premier League at +4.

Arsenal won its last matchup 3-0 over Nottingham Forest at home on September 13. Nottingham Forest was outshot in the matchup, five to 16. Martin Zubimendi for two goals in the match against Nottingham Forest. Manchester City secured a 3-0 home victory over Manchester United in its last match on September 14, despite being outshot 12 to 10. Erling Haaland registered two goals to lead Manchester City in the match.

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Arsenal vs. Manchester City Odds & Betting Lines

Arsenal vs Manchester City Betting Information updated as of September 21, 2025, 6:39 AM ET.
Moneyline Favorite Moneyline Underdog Total Over Total Odds Under Total Odds
Arsenal -109 Manchester City +279 2.5 -132 +104

Arsenal vs. Manchester City Prediction & Pick

  • Moneyline Pick: Arsenal -109
  • Total Pick: Over 2.5 goals
  • Score Prediction: Arsenal 2, Manchester City 1

Arsenal vs. Manchester City Match Info

  • Match Day: Sunday, September 21, 2025
  • Match Time: 11:30 AM ET
  • Location: London, England
  • Stadium: Emirates Stadium
  • TV: Peacock Premium
  • Live Boxscore: FOX Sports

Arsenal's Moneyline Performance

  • So far this season, Arsenal has been favored in three matches, and won every time.
  • Arsenal has won each of its three games as a -109 favorite or greater.
  • Arsenal's chances of winning this match are 52.2%, according to the moneyline.

Arsenal's Key Players

Name Games Goals Assists Shots Chances Created
Viktor Gyokeres 4 3 0 7 2
Jurrien Timber 4 2 1 2 3
Riccardo Calafiori 4 1 2 4 1
Martin Zubimendi 4 2 0 4 1
Leandro Trossard 4 0 1 0 1

Manchester City's Moneyline Performance

  • Manchester City has not yet played a match as an underdog this season.
  • Thus far this season, Manchester City has not been this big an underdog (+279).
  • According to the moneyline, Manchester City's chances of winning this match are 26.4%.

Manchester City's Key Players

Name Games Goals Assists Shots Chances Created
Erling Haaland 4 5 0 15 2
Jeremy Doku 4 0 2 0 6
Tijani Reijnders 4 1 1 5 3
Phil Foden 2 1 0 3 2
Rayan Cherki 2 1 0 1 1

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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