Sabres vs. Blues Prediction, Odds, Picks - Nov. 6

Sabres vs. Blues Prediction, Odds, Picks - Nov. 6

Updated Nov. 6, 2025 6:14 p.m. ET
Data Skrive

The Buffalo Sabres and St. Louis Blues are scheduled to face off at KeyBank Center on Thursday, Nov. 6 at 7 p.m. ET, a matchup that features Tage Thompson and Jordan Kyrou as two of the top players you'll want to keep tabs on. Take a look at everything you need to know about the Sabres-Blues game, from the puck lined, moneyline, total Over/Under and expert picks, as well as TV channel and streaming information.

Sabres vs. Blues Game Information and TV Channel

  • When: Thursday, November 6, 2025 at 7 p.m. ET
  • Where: KeyBank Center in Buffalo, New York
  • TV: ESPN+
  • Live Boxscore: FOX Sports
Sabres vs Blues Betting Information
Favorite Puck Line Favorite Puck Line Odds Underdog Puck Line Odds Total Over Total Odds Under Total Odds Favorite Moneyline Underdog Moneyline
Sabres -1.5 180 -218 6.5 100 -120 -142 +120

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Sabres vs. Blues Prediction

ATS Pick: Sabres (- 1.5)
O/U Pick: Over (6.5)
Score Prediction: Sabres 5 - Blues 2

Sabres vs. Blues Betting Insights

  • Buffalo's games this season have finished above this matchup's total of 6.5 goals six times.
  • St. Louis has combined with its opponent to score over 6.5 goals in eight of 14 games this season.
  • The two teams average 5.6 goals per game combined, 0.9 fewer than this game's over/under.
  • These two teams allow a combined 7.2 goals per game, 0.7 more than this game'sgame's total.
  • The Sabres are 24th in goals scored in the league, and the Blues are 22nd.
  • The Blues are 32nd in the league in goals conceded, and the Sabres are 14th.

Sabres Stats

  • The Sabres' 37 total goals (2.8 per game) make them the 24th-ranked scoring team in the league.
  • Buffalo ranks 14th in goals against, allowing 40 total goals (3.1 per game) in NHL play.
  • Their -3 goal differential ranks 20th in the league.
  • The eight power-play goals Buffalo has recorded this season (to rank 19th in the NHL) have come on 42 chances.
  • The Sabres have the league's 20th-ranked power-play conversion rate (19.05%).
  • Buffalo has scored two shorthanded goals this season (fifth among all NHL squads).

Sabres Leaders

Name Games Goals Assists Points Giveaways Takeaways Faceoff Win %
Alex Tuch 13 4 7 11 9 3 30%
Tage Thompson 13 5 5 10 13 9 51.2%
Josh Doan 13 5 4 9 13 6 66.7%
Rasmus Dahlin 13 1 8 9 30 6 -
Zachary Benson 8 0 9 9 7 5 66.7%

Sabres Player Props

Blues Stats

  • With 38 goals (2.7 per game), the Blues have the league's 22nd-ranked offense.
  • St. Louis has given up 58 total goals this season (4.1 per game), ranking 32nd in the NHL.
  • They have the 32nd-ranked goal differential in the league at -20.
  • St. Louis has nine power-play goals (on 39 chances), 15th in the NHL.
  • The Blues have the NHL's ninth-best power-play percentage (23.08).
  • This season, St. Louis has one shorthanded goal (10th in league).

Blues Leaders

Name Games Goals Assists Points Giveaways Takeaways Faceoff Win %
Pius Suter 14 5 4 9 6 6 47.7%
Robert Thomas 10 2 6 8 18 6 49.1%
Jimmy Snuggerud 14 4 4 8 6 8 100%
Jordan Kyrou 14 4 4 8 4 6 0%
Jake Neighbours 8 6 1 7 4 0 100%

Blues Player Props

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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